Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4136254 | 1.00 | CHRM1 (0.53) | CHRM1CHRM3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4131991 | 0.86 | SLC6A2 (0.50) | CHRM1CHRM3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4131984 | 0.86 | SLC6A2 (0.50) | CHRM1CHRM3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4144918 | 0.86 | SLC6A2 (0.47) | CHRM1CHRM3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4144913 | 0.86 | SLC6A2 (0.47) | CHRM1CHRM3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4124163 | 0.86 | CHRNB2 (0.56) | CHRM3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL4124168 | 0.86 | CHRNB2 (0.56) | CHRM3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL4138856 | 0.85 | SLC6A2 (0.47) | CHRM1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL4131943 | 0.85 | SLC6A2 (0.47) | CHRM3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL4137148 | 0.85 | SLC6A2 (0.51) | CHRM1CHRM3SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215857-A1 | Therapeutic Pyrrolidines | PFIZER PRODUCTS INC. (US) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215857-A1 | Therapeutic Pyrrolidines | OPRL1, HTR5A, OPRD1 | CHRM1 264/4885CHRM3 1033/4885SLC6A2 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.