Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 10/20 | 0.50 |
| ▸ | NOS1 | P29475 | 9/20 | 0.50 |
| ▸ | NOS3 | P29474 | 6/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836532 | 0.91 | NOS2 (0.49) | NOS2NOS1NOS3CYP2C9FLT3 | |
| SCHEMBL4148356 | 0.91 | NOS2 (0.52) | NOS2NOS1NOS3CYP2C9FLT3 | |
| SCHEMBL5034557 | 0.91 | NOS2 (0.48) | NOS2NOS1NOS3CYP2C9FLT3 | |
| SCHEMBL2832523 | 0.89 | NOS1 (0.53) | NOS2NOS1NOS3CYP2C9FLT3 | |
| SCHEMBL2831944 | 0.89 | NOS1 (0.49) | NOS2NOS1NOS3CYP2C9LMNA | |
| SCHEMBL4134847 | 0.88 | NOS2 (0.52) | NOS2NOS1NOS3CYP2C9FGFR3 | |
| SCHEMBL2831974 | 0.88 | NOS1 (0.55) | NOS2NOS1NOS3CYP2C9LMNA | |
| SCHEMBL2839208 | 0.87 | NOS2 (0.50) | NOS2NOS1NOS3CYP2C9MAPT | |
| SCHEMBL2839097 | 0.87 | NOS1 (0.48) | NOS2NOS1NOS3CYP2C9LMNA | |
| SCHEMBL4134667 | 0.87 | NOS2 (0.49) | NOS2NOS1NOS3CYP2C9FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036482-A1 | Imidazopyridine-derivatives as inductible no-synthase inhibitors | ALTANA PHARMA AG (DE) | 2009-02-05 | — | — | US | disclosed |
| US-7468377-B2 | Imidazopyridine-derivatives as inductible no-synthase inhibitors | ALTANA PHARMA AG (DE) | 2008-12-23 | — | — | US | disclosed |
| EP-1675854-B1 | IMIDAZOPYRIDINE-DERIVATIVES AS INDUCTIBLE NO-SYNTHASE INHIBITORS | NYCOMED GMBH (DE) | 2008-06-25 | — | — | EP | disclosed |
| US-20070043073-A1 | Imidazopyridine-derivatives as inductible no-synthase inhibitors | ALTANA PHARMA AG (DE) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036482-A1 | Imidazopyridine-derivatives as inductible no-synthase inhibitors | NOS2, NOS1, NOS3 | NOS2 1/4885NOS1 2/4885NOS3 3/4885 |
| US-20070043073-A1 | Imidazopyridine-derivatives as inductible no-synthase inhibitors | NOS2, NOS1, NOS3 | NOS2 1/4885NOS1 2/4885NOS3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.