SCHEMBL4137790

SCHEMBL4137790

NC(=O)CC[C@H](NS(=O)(=O)c1ccc(N)c2ccccc12)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 13/20 0.60
MMP2 P08253 12/20 0.60
L3MBTL1 Q9Y468 1/20 0.56
MMP8 P22894 4/20 0.47
MMP13 P45452 1/20 0.47
ADAMTS4 O75173 1/20 0.47
MMP12 P39900 3/20 0.44
MMP14 P50281 3/20 0.44
KMT2A Q03164 1/20 0.43
NSD2 O96028 1/20 0.42
CA2 P00918 2/20 0.42
CA1 P00915 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3465132 1.00 MMP9 (0.60) MMP9MMP2L3MBTL1MMP8MMP13
SCHEMBL5706285 0.91 MMP9 (0.57) MMP9MMP2L3MBTL1MMP8MMP13
SCHEMBL3863364 0.91 MMP9 (0.57) MMP9MMP2L3MBTL1MMP8MMP13
SCHEMBL5149287 0.86 MMP9 (0.44) MMP9MMP2L3MBTL1MMP8MMP13
SCHEMBL6266412 0.85 PKLR (0.50) MMP9MMP2NSD2
SCHEMBL1168298 0.84 MMP2 (0.46) MMP9MMP2MMP8MMP12MMP14
SCHEMBL319322 0.84 MMP9 (0.61) MMP9MMP2MMP8MMP13ADAMTS4
SCHEMBL9670221 0.84 NSD2 (0.45) NSD2
SCHEMBL180020 0.84 NSD2 (0.45) MMP9MMP2ADAMTS4NSD2
SCHEMBL8842858 0.84 NSD2 (0.45) MMP9L3MBTL1MMP8MMP13ADAMTS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541633-A Ink jet printing of concealed images on carbonless paper XEROX CORPORATION (US) 1996-07-30 US claimed
US-5286286-A Containing diethylene glycol monobutyl ether, glycerol, and a dansyl or porphyrin chromophores XEROX CORPORATION (US) 1994-02-15 US claimed
US-20190137505-A1 BIOMARKERS OF METHYLGLYOXAL AND RELATED METHODS THEREOF UNIV ARIZONA (US) 2019-05-09 US disclosed
WO-2017027611-A2 BIOMARKERS OF METHYLGLYOXAL AND RELATED METHODS THEREOF THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2017-02-16 WO disclosed
US-20090008452-A1 PRODUCT PACKAGING INCLUDING DIGITAL DATA VERIFICATION TECHNOLOGIES, INC. (US) 2009-01-08 US disclosed
US-20080011853-A1 Product Packaging Including Digital Data VERIFICATION TECHNOLOGIES, INC. (US) 2008-01-17 US disclosed
US-7237720-B2 Product packaging including digital data VERIFICATION TECHNOLOGIES, INC. (US) 2007-07-03 US disclosed
US-20070001011-A1 Product packaging including digital data VERIFICATION TECHNOLOGIES, INC. (US) 2007-01-04 US disclosed
EP-1200932-B1 AUTHENTICATION DEVICE AND METHOD OF AUTHENTICATING PRODUCTS OR PRODUCT PACKAGING SUN CHEMICAL BV (NL) 2006-09-13 EP disclosed
US-7079230-B1 Portable authentication device and method of authenticating products or product packaging SUN CHEMICAL B.V. (NL) 2006-07-18 US disclosed
US-20050243305-A1 Tamper-resistant authentication mark for use in product or product packaging authentication VIG RAKESH 2005-11-03 US disclosed
US-20030176355-A1 Synthetic proteins for in vivo drug delivery and tissue augmentation PROTEIN POLYMER TECHNOLOGIES, INC. 2003-09-18 US disclosed
US-20030112423-A1 On-line verification of an authentication mark applied to products or product packaging VERIFICATION TECHNOLOGIES, INC. 2003-06-19 US disclosed
WO-2001006453-A9 PORTABLE AUTHENTICATION DEVICE AND METHOD OF AUTHENTICATING PRODUCTS OR PRODUCT PACKAGING VERIFICATION TECHNOLOGIES INC (US) 2002-07-25 WO disclosed
EP-1200932-A1 PORTABLE AUTHENTICATION DEVICE AND METHOD OF AUTHENTICATING PRODUCTS OR PRODUCT PACKAGING Verification Technologies, Inc. d/b/a Veritec (US) 2002-05-02 EP disclosed
US-6380154-B1 ADMINISTERING AN AMINO ACID SEQUENCE WHICH PROMOTES PROTEIN CRYSTALLIZATION, AND AN AMINO ACID SEQUENCE ELEMENT SUCH AS ELASTIN-LIKE ELEMENT, COLLAGEN-LIKE ELEMENT OR A KERATIN-LIKE ELEMENT, AND A BIOLOGICALLY ACTIVE SUBSTANCE PROTEIN POLYMER TECHNOLOGIES, INC. 2002-04-30 US disclosed
US-20020045567-A1 SYNTHETIC PROTEINS FOR IN VIVO DRUG DELIVERY AND TISSUE AUGMENTATION SPINE WAVE, INC. 2002-04-18 US disclosed
WO-2001006453-A1 PORTABLE AUTHENTICATION DEVICE AND METHOD OF AUTHENTICATING PRODUCTS OR PRODUCT PACKAGING VERIFICATION TECHNOLOGIES, INC. D/B/A VERITEC (US) 2001-01-25 WO disclosed
US-5541633-A Ink jet printing of concealed images on carbonless paper XEROX CORPORATION (US) 1996-07-30 US disclosed
US-5286286-A Containing diethylene glycol monobutyl ether, glycerol, and a dansyl or porphyrin chromophores XEROX CORPORATION (US) 1994-02-15 US disclosed