Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.43 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.41 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087534 | 0.80 | HSD17B1 (0.41) | HSD17B1ESR1PTP4A3HSD17B2ESR2 | |
| SCHEMBL28039573 | 0.80 | CYP2A6 (0.39) | ESR1ESR2MEN1ALDH1A1HPGD | |
| SCHEMBL11522473 | 0.79 | ESR1 (0.53) | HSD17B1ESR1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL13739868 | 0.77 | MAPT (0.40) | HSD17B1ESR1HSD17B2ESR2GAA | |
| SCHEMBL9755135 | 0.76 | HSD17B1 (0.70) | HSD17B1ESR1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL119652 | 0.75 | HSD17B1 (0.58) | HSD17B1ESR1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL11521978 | 0.75 | HSD17B1 (0.58) | HSD17B1ESR1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL11525349 | 0.75 | HSD17B1 (0.58) | HSD17B1ESR1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL10205948 | 0.74 | ESR1 (0.66) | HSD17B1ESR1PTP4A3PTP4A2PTP4A1 | |
| SCHEMBL9669889 | 0.74 | HSD17B1 (0.53) | HSD17B1ESR1PTP4A3PTP4A2PTP4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952207-B2 | Copper-catalyzed C—H bond arylation | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-02-10 | — | — | US | disclosed |
| US-8952207-B2 | Copper-catalyzed C—H bond arylation | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-02-10 | — | — | US | disclosed |
| US-8952207-B2 | Copper-catalyzed C—H bond arylation | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-02-10 | — | — | US | disclosed |
| US-20090076266-A1 | COPPER-CATALYZED C-H BOND ARYLATION | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2009-03-19 | — | — | US | disclosed |
| US-20090076266-A1 | COPPER-CATALYZED C-H BOND ARYLATION | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2009-03-19 | — | — | US | disclosed |
| US-20090076266-A1 | COPPER-CATALYZED C-H BOND ARYLATION | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076266-A1 | COPPER-CATALYZED C-H BOND ARYLATION | AOC2, AOC3, DBH | HSD17B1 587/4885ESR1 792/4885PTP4A3 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.