Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 12/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 11/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19741486 | 0.86 | HSD17B1 (0.56) | HSD17B1HSD17B2CNR1MEN1ALDH1A1 | |
| SCHEMBL10455681 | 0.82 | HSD17B1 (0.59) | HSD17B1HSD17B2CNR1MEN1ALDH1A1 | |
| SCHEMBL147294 | 0.80 | HSD17B1 (0.49) | HSD17B1HSD17B2CNR1PGRMEN1 | |
| SCHEMBL13999265 | 0.79 | HSD17B1 (0.52) | HSD17B1HSD17B2CYP2A6PGR | |
| SCHEMBL27688177 | 0.79 | CYP2A6 (0.61) | HSD17B1HSD17B2CYP2A6MEN1ALDH1A1 | |
| SCHEMBL9429775 | 0.77 | ALDH1A1 (0.50) | HSD17B1HSD17B2CYP2A6CNR1MEN1 | |
| SCHEMBL12529379 | 0.77 | HSD17B1 (0.47) | HSD17B1HSD17B2CNR1MEN1ALDH1A1 | |
| SCHEMBL5673936 | 0.77 | HSD17B1 (0.93) | HSD17B1HSD17B2 | |
| SCHEMBL29668098 | 0.77 | ALDH1A1 (0.50) | HSD17B1HSD17B2CYP2A6CNR1MEN1 | |
| SCHEMBL28530288 | 0.77 | SNCA (0.50) | HSD17B1HSD17B2CNR1PGRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952207-B2 | Copper-catalyzed C—H bond arylation | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-02-10 | — | — | US | disclosed |
| US-8952207-B2 | Copper-catalyzed C—H bond arylation | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-02-10 | — | — | US | disclosed |
| US-8952207-B2 | Copper-catalyzed C—H bond arylation | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-02-10 | — | — | US | disclosed |
| US-20090076266-A1 | COPPER-CATALYZED C-H BOND ARYLATION | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2009-03-19 | — | — | US | disclosed |
| US-20090076266-A1 | COPPER-CATALYZED C-H BOND ARYLATION | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2009-03-19 | — | — | US | disclosed |
| US-20090076266-A1 | COPPER-CATALYZED C-H BOND ARYLATION | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076266-A1 | COPPER-CATALYZED C-H BOND ARYLATION | AOC2, AOC3, DBH | HSD17B1 587/4885HSD17B2 493/4885CYP2A6 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.