Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3920445 | 0.82 | SLC6A9 (0.79) | SLC6A9GPR55SLC6A5 | |
| SCHEMBL3920703 | 0.80 | SLC6A9 (0.85) | SLC6A9GPR55SLC6A5 | |
| SCHEMBL3927742 | 0.79 | SLC6A9 (0.76) | SLC6A9GPR55SLC6A5 | |
| SCHEMBL12560142 | 0.78 | SLC6A9 (0.62) | SLC6A9 | |
| SCHEMBL3918534 | 0.77 | SLC6A9 (0.80) | SLC6A9GPR55SLC6A5 | |
| SCHEMBL4421735 | 0.76 | SLC6A9 (0.63) | SLC6A9GPR55 | |
| SCHEMBL4138700 | 0.76 | SLC6A9 (0.71) | SLC6A9GPR55SLC6A5 | |
| SCHEMBL4938236 | 0.76 | SLC6A9 (0.80) | SLC6A9GPR55SLC6A5 | |
| SCHEMBL3922540 | 0.75 | SLC6A9 (0.80) | SLC6A9GPR55SLC6A5 | |
| SCHEMBL3918531 | 0.75 | SLC6A9 (0.75) | SLC6A9GPR55SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595314-B2 | Benzoyl-piperazine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-09-29 | — | — | US | disclosed |
| US-20090192136-A1 | BENZOYL-PIPERAZINE DERIVATIVES | ALBERATI-GIANI DANIELA | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192136-A1 | BENZOYL-PIPERAZINE DERIVATIVES | OPRL1, ACHE, PNMT | SLC6A9 4305/4885GPR55 194/4885SLC6A5 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.