SCHEMBL4138869

SCHEMBL4138869

O=C(O)c1ccc(-n2nnnc2C(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.54
PTGS2 P35354 1/20 0.50
ALDH1A1 P00352 5/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
MAPK1 P28482 1/20 0.48
PPARG P37231 1/20 0.48
HTT P42858 2/20 0.47
LMNA P02545 2/20 0.47
TP53 P04637 2/20 0.47
MAPT P10636 1/20 0.47
GFER P55789 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
EP300 Q09472 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44
RECQL P46063 1/20 0.44
POLB P06746 1/20 0.44
TSHR P16473 2/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17153881 0.85 HPGD (0.48) HPGDPTGS2ALDH1A1MEN1KMT2A
SCHEMBL2211636 0.85 ALDH1A1 (0.53) HPGDALDH1A1MEN1KMT2AHTT
SCHEMBL15569357 0.84 LMNA (0.42) HPGDPTGS2ALDH1A1MEN1KMT2A
SCHEMBL278889 0.81 HPGD (0.52) HPGDPTGS2ALDH1A1MEN1KMT2A
SCHEMBL28746954 0.81 HPGD (0.52) HPGDPTGS2ALDH1A1MEN1KMT2A
SCHEMBL1974715 0.81 LMNA (0.65) HPGDPTGS2ALDH1A1MEN1KMT2A
SCHEMBL10467593 0.81 HPGD (0.52) HPGDPTGS2ALDH1A1MEN1KMT2A
SCHEMBL17768306 0.80 ALDH1A1 (0.48) HPGDALDH1A1HTTLMNATP53
SCHEMBL8162513 0.80 LMNA (0.52) HPGDPTGS2ALDH1A1MEN1KMT2A
SCHEMBL28746953 0.79 HPGD (0.51) HPGDPTGS2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090087988-A1 POLISHING LIQUID AND POLISHING METHOD FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087988-A1 POLISHING LIQUID AND POLISHING METHOD FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087988-A1 POLISHING LIQUID AND POLISHING METHOD FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed