Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131898 | 0.94 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL4130236 | 0.89 | LMNA (0.62) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL11573009 | 0.83 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL11457992 | 0.80 | LMNA (0.81) | ALDH1A1SMN1; SMN2CYP19A1KMT2AKDM4E | |
| SCHEMBL31089791 | 0.79 | LMNA (0.59) | ALDH1A1SMN1; SMN2CYP19A1KMT2AKDM4E | |
| SCHEMBL11015595 | 0.79 | CA12 (0.65) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL11107948 | 0.79 | LMNA (0.62) | ALDH1A1SMN1; SMN2CYP19A1KMT2AKDM4E | |
| SCHEMBL4801989 | 0.78 | LMNA (0.57) | ALDH1A1SMN1; SMN2CYP19A1KMT2AKDM4E | |
| SCHEMBL4801999 | 0.78 | LMNA (0.57) | ALDH1A1SMN1; SMN2CYP19A1KMT2AKDM4E | |
| SCHEMBL4797433 | 0.78 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2CYP19A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066643-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008062012-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |