Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31105945 | 0.80 | KDM4E (0.36) | ALDH1A1KDM4EKMT2AENPP2HDAC6 | |
| SCHEMBL25924621 | 0.79 | KDM4E (0.36) | ALDH1A1KDM4EKMT2APOLBENPP2 | |
| SCHEMBL20595463 | 0.76 | CTSK (0.34) | ALDH1A1GLAKDM4EHSD17B10 | |
| SCHEMBL28948622 | 0.76 | AR (0.35) | ALDH1A1GLAKDM4EMAPTRAB9A | |
| SCHEMBL25925090 | 0.74 | ALDH1A1 (0.36) | ALDH1A1GLAKDM4EKMT2AENPP2 | |
| SCHEMBL19208077 | 0.74 | ADORA3 (0.40) | ALDH1A1KDM4EMAPTRAB9AKMT2A | |
| SCHEMBL4134200 | 0.73 | FNTA (0.48) | ALDH1A1GLAKDM4EMAPTRAB9A | |
| SCHEMBL24621132 | 0.72 | AR (0.40) | ALDH1A1GLAKDM4EAR | |
| SCHEMBL28803316 | 0.72 | ALDH1A1 (0.38) | ALDH1A1GLAKDM4EMAPTRAB9A | |
| SCHEMBL19208455 | 0.72 | KDM4E (0.35) | ALDH1A1KDM4EKMT2AENPP2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131662-A1 | Compositions And Methods Pertaining To PNA Synthons And Oligomers Comprising A Universal Base | LIFE TECHNOLOGIES CORPORATION, A DELAWARE CORPORATION (US) | 2009-05-21 | — | — | US | disclosed |
| US-7482353-B2 | Compositions and methods pertaining to PNA synthons and oligomers comprising a universal base | APPLIED BIOSYSTEMS INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20060287526-A1 | Compositions and methods pertaining to PNA synthons and oligomers comprising a universal base | APPLERA CORPORATION (US) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131662-A1 | Compositions And Methods Pertaining To PNA Synthons And Oligomers Comprising A Universal Base | DNMT3A, DNTT, POLI | ALDH1A1 4607/4885GLA 1455/4885KDM4E 4709/4885 |
| US-20060287526-A1 | Compositions and methods pertaining to PNA synthons and oligomers comprising a universal base | DNMT3A, DNTT, POLI | ALDH1A1 4607/4885GLA 1455/4885KDM4E 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.