SCHEMBL4140209

SCHEMBL4140209

CC(=NO)c1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 2/20 0.50
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 1/20 0.47
ALDH1A1 P00352 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HTT P42858 1/20 0.47
CYP2C19 P33261 3/20 0.46
CASP3 P42574 2/20 0.46
SENP7 Q9BQF6 2/20 0.46
SENP6 Q9GZR1 2/20 0.46
NPC1 O15118 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2D6 P10635 1/20 0.46
NFKB1 P19838 1/20 0.46
RAB9A P51151 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4140208 1.00 CA9 (0.50) CA9MEN1KMT2AMAPTALDH1A1
SCHEMBL12360950 0.87 CA9 (0.52) CA9MEN1KMT2AMAPTALDH1A1
SCHEMBL14298196 0.87 CA9 (0.52) CA9MEN1KMT2AMAPTALDH1A1
Bromobenzene SCHEMBL28232899 0.84 CYP2C19 (0.50) CA9MEN1KMT2AMAPTALDH1A1
SCHEMBL24329691 0.80 MEN1 (0.47) CA9MEN1KMT2AMAPTALDH1A1
SCHEMBL13645704 0.79 CA9 (0.47) CA9KMT2AMAPTALDH1A1NPSR1
SCHEMBL6053302 0.78 MAPT (0.50) CA9MEN1KMT2AMAPTALDH1A1
SCHEMBL5415127 0.78 MAPT (0.50) CA9MEN1KMT2AMAPTALDH1A1
SCHEMBL14626976 0.77 ESR1 (0.48) CA9MEN1KMT2AMAPTALDH1A1
SCHEMBL467701 0.77 ESR1 (0.48) CA9MEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117720433-A Preparation method and application of oxime carbonate compound 河南农业大学 2024-03-19 CN claimed
CN-112574135-B 4-aryl-5-thioether-2-difluoromethyl oxazole, and derivatives and synthesis method thereof 湖南工程学院 2022-09-23 CN claimed
CN-112574135-A 4-aryl-5-thioether-2-difluoromethyl oxazole, and derivatives and synthesis method thereof 湖南工程学院 2021-03-30 CN claimed
CN-110294758-A 2- replaces 5,6- dihydro-pyrazolo [5,1- α] isoquinolin, derivative and its synthetic method 湘潭大学 2019-10-01 CN claimed
CN-109705146-A 2- amino benzo [4,5] thieno [3,2-d] thiazole, derivative and its synthetic method 湘潭大学 2019-05-03 CN claimed
CN-108822135-A A kind of synthetic method of the cyclosubstituted thieno of azepine [3,2-d] thiazole and its derivative 湘潭大学 2018-11-16 CN claimed
CN-106518707-B Method for preparing amide 南京工业大学 2018-02-06 CN claimed
CN-107011201-A Preparation method of amide 南京工业大学 2017-08-04 CN claimed
CN-106518707-A Method for preparing amide 南京工业大学 2017-03-22 CN claimed
US-20250221979-A1 NOVEL HETEROCYCLIC COMPOUND SHOUYAO HOLDINGS BEIJING CO LTD (CN) 2025-07-10 US disclosed
EP-4501912-A1 NOVEL HETEROCYCLIC COMPOUND Shouyao Holdings (Beijing) Co., Ltd. (CN) 2025-02-05 EP disclosed
CN-118475560-A Novel heterocyclic compound 首药控股(北京)股份有限公司 2024-08-09 CN disclosed
CN-117720433-A Preparation method and application of oxime carbonate compound 河南农业大学 2024-03-19 CN disclosed
WO-2023185811-A1 NOVEL HETEROCYCLIC COMPOUND 首药控股(北京)股份有限公司 2023-10-05 WO disclosed
US-5663185-A FUNGICIDES, INSECTICIDES, NEMATOCIDES BASF AKTIENGESELLSCHAFT (DE) 1997-09-02 US disclosed
US-5536734-A FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-07-16 US disclosed
EP-0579071-A2 Heteroaromatic compounds and plant-protecting agents containing them BASF Aktiengesellschaft (DE) 1994-01-19 EP disclosed
EP-0508999-A1 PHARMACEUTICALLY ACTIVE NORMONYL COMPOUNDS Beecham Group p.l.c. (GB) 1992-10-21 EP disclosed
WO-1991009855-A1 PHARMACEUTICALLY ACTIVE NORMONYL COMPOUNDS BEECHAM GROUP PLC (GB) 1991-07-11 WO disclosed
US-4264498-A REACTED WITH AN ACID, ITS ACID HALIDE, OR ANHYDRIDE IN THE PRESENCE OF BORON TRIHALIDE AND AN ORGANIC BASE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250221979-A1 NOVEL HETEROCYCLIC COMPOUND MAPT, MNAT1, MAT2A CA9 3422/4885MEN1 662/4885KMT2A 723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.