Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14298196 | 0.91 | CA9 (0.52) | CA9POLBCASP3GFERSENP8 | |
| SCHEMBL12360950 | 0.91 | CA9 (0.52) | CA9POLBCASP3GFERSENP8 | |
| SCHEMBL8306282 | 0.91 | CA9 (0.51) | CA9POLBCASP3GFERSENP8 | |
| SCHEMBL3368876 | 0.91 | SMN1; SMN2 (0.56) | CA9POLBCASP3GFERSENP8 | |
| SCHEMBL4316450 | 0.91 | SMN1; SMN2 (0.56) | CA9POLBCASP3GFERSENP8 | |
| SCHEMBL5609938 | 0.89 | LMNA (0.50) | CA9POLBCASP3GFERSENP8 | |
| SCHEMBL8308938 | 0.87 | CYP17A1 (0.46) | CA9MAPTCYP3A4KDM4ELMNA | |
| SCHEMBL5608949 | 0.85 | SMN1; SMN2 (0.59) | CA9CASP3SENP8SENP7SENP6 | |
| SCHEMBL8309008 | 0.83 | KIF11 (0.50) | CA9RAB9ALMNAALDH1A1 | |
| SCHEMBL27364938 | 0.83 | HRH3 (0.54) | CA9KDM4EHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601873-B2 | Method of manufacturing 3,3′,4,4′-tetraaminobiphenyl | SHOWA DENKO K.K. (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20090149676-A1 | METHOD OF MANUFACTURING 3, 3' , 4, 4'-TETRAAMINOBIPHENYL | SHOWA DENKO K. K. (JP) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149676-A1 | METHOD OF MANUFACTURING 3, 3' , 4, 4'-TETRAAMINOBIPHENYL | BRI3BP, TH, TST | CA9 3124/4885POLB 2975/4885CASP3 1063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.