Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5789028 | 0.86 | HRH4 (0.57) | HRH4MEN1ALDH1A1GAAMAPT | |
| SCHEMBL1458548 | 0.77 | HRH4 (0.61) | HRH4MEN1ALDH1A1GAAALOX15 | |
| SCHEMBL11837825 | 0.77 | ALDH1A1 (0.50) | MEN1ALDH1A1GAAMAPTALOX15 | |
| SCHEMBL6262576 | 0.75 | HRH4 (0.54) | HRH4MEN1ALDH1A1GAAMAPT | |
| SCHEMBL5847761 | 0.75 | HRH4 (0.54) | HRH4MEN1ALDH1A1GAAMAPT | |
| SCHEMBL10377507 | 0.74 | HRH4 (0.62) | HRH4MEN1ALDH1A1GAAALOX15 | |
| SCHEMBL29563775 | 0.74 | TERT (0.48) | HRH4MEN1ALDH1A1GAAMAPT | |
| SCHEMBL30296930 | 0.73 | HRH4 (0.61) | HRH4MEN1ALDH1A1GAAALOX15 | |
| SCHEMBL4120084 | 0.73 | TERT (0.47) | HRH4MEN1ALDH1A1GAAMAPT | |
| SCHEMBL1097561 | 0.72 | CHKA (0.52) | HRH4MEN1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140142124-A1 | Compositions for Topical Application Having Androgenic Actions | AVENTIS PHARMA SA (DE) | 2014-05-22 | — | — | US | claimed |
| US-20120277235-A1 | Compositions For Topical Application Having Androgenic Actions | AVENTIS PHARMA S.A | 2012-11-01 | — | — | US | claimed |
| US-20090093487-A1 | Compositions for topical application having androgenic actions | AVENTIS PHARMA S.A. | 2009-04-09 | — | — | US | claimed |
| EP-1123082-B1 | PREPARATIONS FOR TOPICAL APPLICATION OF SUBSTANCES HAVING ANTIANDROGENIC EFFECT | AVENTIS PHARMA SA (FR) | 2006-03-01 | — | — | EP | claimed |
| US-20050175647-A1 | Compositions for topical application having androgenic actions | AVENTIS PHARMA DEUTSCHLAND GMBH. | 2005-08-11 | — | — | US | claimed |
| US-20030083322-A1 | COMPOSITIONS FOR TOPICAL APPLICATION HAVING ANDREGENIC ACTIONS | AVENTIS PHARMA S.A. (FR) | 2003-05-01 | — | — | US | claimed |
| EP-1123082-A1 | PREPARATIONS FOR TOPICAL APPLICATION OF SUBSTANCES HAVING ANTIANDROGENIC EFFECT | Aventis Pharma Deutschland GmbH (DE) | 2001-08-16 | — | — | EP | claimed |
| EP-0879052-B1 | PREPARATIONS STIMULATING NAIL GROWTH | AVENTIS PHARMA GMBH (DE) | 2000-12-20 | — | — | EP | claimed |
| WO-2000024366-A1 | PREPARATIONS FOR TOPICAL APPLICATION OF SUBSTANCES HAVING ANTIANDROGENIC EFFECT | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-05-04 | — | — | WO | claimed |
| US-6007798-A | TOPICAL VARNISH COMPRISING A VASODILATOR COMPOUND IN WATER INSOLUBLE FILM-FORMING RESIN; FUNGICIDES, PROPHYLAXIS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-12-28 | — | — | US | claimed |
| EP-0879052-A1 | PREPARATIONS STIMULATING NAIL GROWTH | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-11-25 | — | — | EP | claimed |
| WO-1997028790-A1 | PREPARATIONS STIMULATING NAIL GROWTH | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-14 | — | — | WO | claimed |
| US-20140142124-A1 | Compositions for Topical Application Having Androgenic Actions | AVENTIS PHARMA SA (DE) | 2014-05-22 | — | — | US | disclosed |
| US-20120277235-A1 | Compositions For Topical Application Having Androgenic Actions | AVENTIS PHARMA S.A | 2012-11-01 | — | — | US | disclosed |
| US-20110065763-A1 | Compositions for Topical Application Having Androgenic Actions | AVENTIS PHARMA S.A | 2011-03-17 | — | — | US | disclosed |
| US-20090093487-A1 | Compositions for topical application having androgenic actions | AVENTIS PHARMA S.A. | 2009-04-09 | — | — | US | disclosed |
| EP-0879052-A1 | PREPARATIONS STIMULATING NAIL GROWTH | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-11-25 | — | — | EP | disclosed |
| US-5801150-A | Aminopyri(mi)dine derivatives combined with amino acids, and pharmacological activities thereof | CAILLOT JEAN-LUC (FR) | 1998-09-01 | — | — | US | disclosed |
| WO-1997028790-A1 | PREPARATIONS STIMULATING NAIL GROWTH | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-14 | — | — | WO | disclosed |
| WO-1992021317-A1 | PYRIDINE 1-OXIDE BASED COMPOSITION FOR COMBATTING HAIR LOSS AND FOR INDUCING AND STIMULATING HAIR GROWTH | L'OREAL (FR) | 1992-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083322-A1 | COMPOSITIONS FOR TOPICAL APPLICATION HAVING ANDREGENIC ACTIONS | NR5A1, CYP17A1, CYP19A1 | HRH4 4456/4885MEN1 1263/4885ALDH1A1 1374/4885 |
| US-20090093487-A1 | Compositions for topical application having androgenic actions | NR5A1, CYP17A1, CYP19A1 | HRH4 3495/4885MEN1 909/4885ALDH1A1 429/4885 |
| US-20140142124-A1 | Compositions for Topical Application Having Androgenic Actions | NR5A1, CYP17A1, CYP19A1 | HRH4 3495/4885MEN1 909/4885ALDH1A1 429/4885 |
| US-20110065763-A1 | Compositions for Topical Application Having Androgenic Actions | NR5A1, CYP17A1, CYP19A1 | HRH4 3495/4885MEN1 909/4885ALDH1A1 429/4885 |
| US-20120277235-A1 | Compositions For Topical Application Having Androgenic Actions | NR5A1, CYP17A1, CYP19A1 | HRH4 3342/4885MEN1 1024/4885ALDH1A1 423/4885 |
| US-20050175647-A1 | Compositions for topical application having androgenic actions | NR5A1, CYP17A1, CYP19A1 | HRH4 3495/4885MEN1 909/4885ALDH1A1 429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.