Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4140306 | 0.86 | HRH4 (0.61) | HRH4CRHBPCRHR2SMN1; SMN2MEN1 | |
| SCHEMBL5789968 | 0.82 | CRHBP (0.57) | HRH4CRHBPCRHR2NOS3NOS1 | |
| SCHEMBL17827818 | 0.78 | CRHBP (0.46) | HRH4CRHBPCRHR2SMN1; SMN2MEN1 | |
| SCHEMBL22148449 | 0.76 | HRH4 (0.58) | HRH4CRHBPCRHR2SMN1; SMN2NOS3 | |
| SCHEMBL30788620 | 0.76 | HRH4 (0.58) | HRH4CRHBPCRHR2SMN1; SMN2NOS3 | |
| SCHEMBL10810138 | 0.72 | ALDH1A1 (0.47) | HRH4CRHBPCRHR2SMN1; SMN2MEN1 | |
| SCHEMBL23516878 | 0.72 | MEN1 (0.42) | HRH4CRHBPCRHR2SMN1; SMN2MEN1 | |
| SCHEMBL29762696 | 0.72 | MEN1 (0.42) | HRH4CRHBPCRHR2SMN1; SMN2MEN1 | |
| SCHEMBL6443104 | 0.72 | GRIN2D (0.63) | HRH4 | |
| SCHEMBL14842709 | 0.71 | NOS3 (0.50) | HRH4NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016014-A1 | NOVEL COMPOUNDS OF A 6-METHYL-PYRIMIDINE-2,4-DIAMINE FAMILY, METHOD FOR SYNTHESISING, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | L'OREAL (FR) | 2006-02-16 | — | — | WO | claimed |
| EP-1437348-A1 | 6-methyl-2,4-diamino-pyrimidine derivatives, process for preparation, compositions containing them and their uses as basic neutralising agents | L'OREAL (FR) | 2004-07-14 | — | — | EP | claimed |
| WO-2006016014-A1 | NOVEL COMPOUNDS OF A 6-METHYL-PYRIMIDINE-2,4-DIAMINE FAMILY, METHOD FOR SYNTHESISING, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | L'OREAL (FR) | 2006-02-16 | — | — | WO | disclosed |
| EP-1437348-A1 | 6-methyl-2,4-diamino-pyrimidine derivatives, process for preparation, compositions containing them and their uses as basic neutralising agents | L'OREAL (FR) | 2004-07-14 | — | — | EP | disclosed |