Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4137513 | 1.00 | TRPV1 (0.49) | TRPV1CYP3A4CFTRHTR6 | |
| SCHEMBL4125522 | 0.94 | TRPV1 (0.45) | TRPV1CYP3A4 | |
| SCHEMBL3766306 | 0.90 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL4133142 | 0.90 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL3322270 | 0.84 | TRPV1 (0.54) | TRPV1CYP3A4CFTR | |
| SCHEMBL3327903 | 0.78 | TRPV1 (0.38) | TRPV1 | |
| SCHEMBL2364052 | 0.77 | TRPV1 (0.44) | TRPV1 | |
| SCHEMBL3322248 | 0.76 | TRPV1 (0.80) | TRPV1CYP3A4 | |
| SCHEMBL3319416 | 0.76 | TRPV1 (0.80) | TRPV1CYP3A4 | |
| SCHEMBL3322010 | 0.72 | TRPV1 (0.72) | TRPV1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143423-A1 | SOLID DISPERSION PRODUCT CONTAINING N-ARYL UREA-BASED COMPOUND | ABBOTT GMBH & CO. KG (DE) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143423-A1 | SOLID DISPERSION PRODUCT CONTAINING N-ARYL UREA-BASED COMPOUND | U2SURP, UMPS, HNRNPUL1 | TRPV1 4781/4885CYP3A4 276/4885CFTR 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.