Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962850 | 1.00 | KMT2A (0.51) | KMT2AALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL4628700 | 0.89 | KMT2A (0.58) | KMT2AALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL1709762 | 0.89 | KMT2A (0.58) | KMT2AALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL4628706 | 0.89 | KMT2A (0.58) | KMT2AALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL18117406 | 0.84 | ALDH1A1 (0.48) | KMT2AALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL890199 | 0.84 | ALDH1A1 (0.48) | KMT2AALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL890212 | 0.84 | ALDH1A1 (0.48) | KMT2AALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL27553133 | 0.84 | MEN1 (0.66) | KMT2AMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL24115263 | 0.83 | ALDH1A1 (0.57) | KMT2AALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL13593226 | 0.83 | ALDH1A1 (0.57) | KMT2AALDH1A1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | PFIZER INC | 2009-08-20 | — | — | US | disclosed |
| EP-1963303-A2 | CHEMICAL COMPOUNDS | Pfizer Limited (GB) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007066201-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CXCR1 | KMT2A 3350/4885ALDH1A1 1442/4885MAPT 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.