Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131871 | 0.91 | CA2 (0.68) | CA2MAPK1GRIK1GRIK2SLC1A2 | |
| SCHEMBL27901184 | 0.89 | CA2 (0.77) | CA2MAPK1GRIK1GRIK2SLC1A2 | |
| SCHEMBL14360381 | 0.89 | CA2 (0.77) | CA2MAPK1GRIK1GRIK2SLC1A2 | |
| SCHEMBL14359878 | 0.89 | CA2 (0.77) | CA2MAPK1GRIK1GRIK2SLC1A2 | |
| SCHEMBL10897254 | 0.87 | CA2 (0.81) | CA2MAPK1GRIK1GRIK2SLC1A2 | |
| SCHEMBL28696438 | 0.86 | CHRM1 (0.64) | CA2MAPK1GRIK1GRIK2SLC1A2 | |
| SCHEMBL28775299 | 0.86 | GRIK1 (0.58) | CA2MAPK1GRIK1GRIK2SLC1A2 | |
| SCHEMBL28684295 | 0.86 | GRIK1 (0.58) | CA2MAPK1GRIK1GRIK2SLC1A2 | |
| SCHEMBL5512425 | 0.86 | CHRM1 (0.64) | CA2MAPK1GRIK1GRIK2SLC1A2 | |
| SCHEMBL28705894 | 0.86 | GRIK1 (0.58) | CA2MAPK1GRIK1GRIK2SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114058173-A | Process and composition for producing flexible polyurethane foams | 赢创运营有限公司 | 2022-02-18 | — | — | CN | disclosed |
| EP-2955171-A1 | MANUFACTURE PROCESS OF N-(5-CHLOROSALICYLOYL)-8-AMINOCAPRYLIC ACID | Novartis AG (CH) | 2015-12-16 | — | — | EP | disclosed |
| EP-1838664-B1 | MANUFACTURE PROCESS OF N-SUBSTITUTED SALICYLAMIDES | NOVARTIS AG (CH) | 2015-07-15 | — | — | EP | disclosed |
| US-8461385-B2 | Manufacture process of organic compounds | NOVARTIS AG (CH) | 2013-06-11 | — | — | US | disclosed |
| US-20090253811-A1 | MANUFACTURE PROCESS OF ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-10-08 | — | — | US | disclosed |
| EP-1838664-A1 | MANUFACTURE PROCESS OF N-SUBSTITUTED SALICYLAMIDES | Novartis AG (CH) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006063821-A1 | MANUFACTURE PROCESS OF N-SUBSTITUTED SALICYLAMIDES | NOVARTIS AG (CH) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253811-A1 | MANUFACTURE PROCESS OF ORGANIC COMPOUNDS | NT5C, AADAC, DDC | CA2 77/4885MAPK1 4412/4885GRIK1 2511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.