SCHEMBL414308

SCHEMBL414308

O=C(OP(=O)(O)O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
F2 P00734 1/20 0.56
TSHR P16473 5/20 0.52
ALDH1A1 P00352 5/20 0.50
KMT2A Q03164 3/20 0.50
MAPT P10636 2/20 0.50
POLB P06746 1/20 0.50
TDP1 Q9NUW8 4/20 0.47
TP53 P04637 1/20 0.47
SRC P12931 1/20 0.46
MAPK1 P28482 1/20 0.45
HIF1A Q16665 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
HSD17B10 Q99714 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7187812 0.98 LMNA (0.54) LMNAF2TSHRALDH1A1KMT2A
SCHEMBL27482562 0.98 LMNA (0.54) LMNAF2TSHRALDH1A1KMT2A
Ammonia Solution, Strong SCHEMBL28192864 0.98 LMNA (0.54) LMNAF2TSHRALDH1A1KMT2A
SCHEMBL28303591 0.98 LMNA (0.54) LMNAF2TSHRALDH1A1KMT2A
SCHEMBL6932070 0.98 LMNA (0.54) LMNAF2TSHRALDH1A1KMT2A
Water SCHEMBL18760058 0.98 LMNA (0.54) LMNAF2TSHRALDH1A1KMT2A
SCHEMBL31197306 0.98 LMNA (0.54) LMNAF2TSHRALDH1A1KMT2A
Ammonia Solution, Strong SCHEMBL28113293 0.96 LMNA (0.52) LMNAF2TSHRALDH1A1KMT2A
Acetamide SCHEMBL27694808 0.90 TSHR (0.48) LMNAF2TSHRALDH1A1KMT2A
SCHEMBL27697235 0.88 CA4 (0.42) LMNAF2TSHRALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118141749-A Double-layer microneedle for treating diabetes periodontitis and preparation method and application thereof 兰州大学 2024-06-07 CN claimed
CN-111595980-B Identification method of vibrio strains 山东省海洋生物研究院 2022-06-10 CN claimed
CN-111595980-A Identification method of vibrio strains 山东省海洋生物研究院 2020-08-28 CN claimed
CN-107848954-A Water-soluble L DOPA esters 伯里兰有限责任公司 2018-03-27 CN claimed
EP-3277660-A1 WATER-SOLUBLE L-DOPA ESTERS Berlirem GmbH (DE) 2018-02-07 EP claimed
WO-2016155888-A1 WATER-SOLUBLE L-DOPA ESTERS BERLIREM GMBH (DE) 2016-10-06 WO claimed
CN-103025877-A Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene GENOMATICA INC 2013-04-03 CN claimed
WO-2012018624-A2 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE GENOMATICA, INC. (US) 2012-02-09 WO claimed
CN-119119515-A Method for preparing carboxymethyl xanthan gum-sulfated xanthan gum-methacryloylated gelatin hydrogel scaffold 武汉纺织大学 2024-12-13 CN disclosed
CN-118511352-A Method for manufacturing secondary battery 株式会社LG新能源 2024-08-16 CN disclosed
CN-118511354-A Method for manufacturing secondary battery 株式会社LG新能源 2024-08-16 CN disclosed
CN-118476078-A Method for manufacturing secondary battery 株式会社LG新能源 2024-08-09 CN disclosed
CN-113574419-B Automotive coating with photonic spheres 巴斯夫涂料有限公司 2024-07-12 CN disclosed
CN-115192470-B Oily composition 宝丽化成工业有限公司 2024-06-18 CN disclosed
EP-1503768-A1 INOSITOL PYROPHOSPHATES, AND METHODS OF USE THEREOF GMP Oxycell, Inc. (US) 2005-02-09 EP disclosed
US-20040014642-A1 Supplying oxygen to cells; antiischemic agents; cardiovascular disorders NORMOXYS, INC. 2004-01-22 US disclosed
WO-2003092700-A1 INOSITOL PYROPHOSPHATES, AND METHODS OF USE THEREOF GMP OXYCELL, INC. (US) 2003-11-13 WO disclosed
CN-1253767-A Adhesive compound for tooth KURARAY CO (JP) 2000-05-24 CN disclosed
US-5143720-A Anionic surfactant, acid, food treatment, mouthwash, soap MICROCIDE, INC. (US) 1992-09-01 US disclosed
US-3979462-A Condensation resins of phenols and α,α'-dihydroxy-diisopropyl benzenes BAYER AKTIENGESELLSCHAFT (DT) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014642-A1 Supplying oxygen to cells; antiischemic agents; cardiovascular disorders PPIP5K2, ITPA, DHPS LMNA 1734/4885F2 2374/4885TSHR 4560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.