Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628762 | 0.88 | TRPM8 (0.62) | TRPM8EPHX1HSD17B10TRPV1LMNA | |
| SCHEMBL4149322 | 0.88 | TRPM8 (0.72) | TRPM8EPHX1TRPV1 | |
| SCHEMBL15133466 | 0.86 | TRPM8 (0.62) | TRPM8EPHX1HSD17B10TRPV1LMNA | |
| SCHEMBL2628752 | 0.85 | TRPM8 (0.61) | TRPM8EPHX1TRPV1 | |
| SCHEMBL10072944 | 0.85 | TRPM8 (0.61) | TRPM8EPHX1HSD17B10TRPV1 | |
| SCHEMBL13989030 | 0.84 | TRPM8 (0.57) | TRPM8EPHX1HSD17B10LMNA | |
| SCHEMBL4817890 | 0.84 | TRPM8 (0.73) | TRPM8EPHX1P2RX4 | |
| SCHEMBL10073491 | 0.84 | TRPM8 (0.73) | TRPM8EPHX1P2RX4 | |
| SCHEMBL2628779 | 0.83 | TRPM8 (0.58) | TRPM8EPHX1TRPV1 | |
| SCHEMBL10072943 | 0.83 | TRPM8 (0.75) | TRPM8TRPV1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105237-A1 | Cooling compounds | GIVAUDAN SA (CH) | 2009-04-23 | — | — | US | disclosed |
| EP-1885327-A1 | COOLING COMPOUNDS | Givaudan SA (CH) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006125334-A1 | COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105237-A1 | Cooling compounds | NR1H2, NR1H3, NR1H4 | TRPM8 261/4885EPHX1 1274/4885HSD17B10 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.