Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.73 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4817890 | 1.00 | TRPM8 (0.73) | TRPM8EPHX1MAPTHPGDMEN1 | |
| SCHEMBL2628738 | 0.92 | TRPM8 (0.70) | TRPM8EPHX1MAPTHPGDMEN1 | |
| SCHEMBL4886771 | 0.88 | TRPM8 (0.72) | TRPM8EPHX1MAPTHPGDMEN1 | |
| SCHEMBL10073486 | 0.88 | TRPM8 (0.75) | TRPM8EPHX1MAPTHPGDMEN1 | |
| SCHEMBL2628672 | 0.88 | TRPM8 (0.75) | TRPM8EPHX1MAPTHPGDMEN1 | |
| SCHEMBL4817319 | 0.88 | TRPM8 (0.75) | TRPM8EPHX1MAPTHPGDMEN1 | |
| SCHEMBL4820732 | 0.88 | TRPM8 (0.75) | TRPM8EPHX1MAPTHPGDMEN1 | |
| SCHEMBL2628758 | 0.86 | TRPM8 (0.73) | TRPM8EPHX1MAPTHPGDMEN1 | |
| SCHEMBL2628747 | 0.86 | TRPM8 (0.73) | TRPM8EPHX1MAPTHPGDMEN1 | |
| SCHEMBL14593913 | 0.86 | TRPM8 (0.73) | TRPM8EPHX1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230363407-A1 | UNWRAPPED HARD CANDY PRODUCT; ISOMALT CONFECTIONERY; METHOD OF MAKING AND USE THEREOF | INTERCONTINENTAL GREAT BRANDS LLC | 2023-11-16 | — | — | US | disclosed |
| US-20230363407-A1 | UNWRAPPED HARD CANDY PRODUCT; ISOMALT CONFECTIONERY; METHOD OF MAKING AND USE THEREOF | INTERCONTINENTAL GREAT BRANDS LLC | 2023-11-16 | — | — | US | disclosed |
| US-20210244044-A1 | CENTER-FILLED CONFECTIONERY PRODUCT; COATED PRODUCT; AND METHODS OF MAKING | INTERCONTINENTAL GREAT BRANDS LLC | 2021-08-12 | — | — | US | disclosed |
| US-20200178558-A1 | CHEWING GUM COMPOSITIONS AND METHODS OF MAKING THEREOF | PERFETTI VAN MELLE BENELUX B.V. (NL) | 2020-06-11 | — | — | US | disclosed |
| US-10278408-B2 | Transparent and transluscent liquid filled candy; process of making thereof; sugar-free liquid edible composition; and use thereof | INTERCONTINENTAL GREAT BRANDS LLC (US) | 2019-05-07 | — | — | US | disclosed |
| EP-1656144-B2 | TRP-P8 ACTIVE COMPOUNDS AND THERAPEUTIC TREATMENT METHODS | GENENTECH INC (US) | 2017-12-20 | — | — | EP | disclosed |
| US-20170079304-A1 | MULTI-TEXTURED CHEWING GUM AND METHODS OF MAKING THEREOF | INTERCONTINENTAL GREAT BRANDS LLC (US) | 2017-03-23 | — | — | US | disclosed |
| US-20170079304-A1 | MULTI-TEXTURED CHEWING GUM AND METHODS OF MAKING THEREOF | INTERCONTINENTAL GREAT BRANDS LLC (US) | 2017-03-23 | — | — | US | disclosed |
| US-20160353765-A1 | COATING FOR EDIBLE CORES; SYSTEM AND PROCESS OF COATING; AND COATED PRODUCTS PREPARED THEREFROM | INTERCONTINENTAL GREAT BRANDS LLC (US) | 2016-12-08 | — | — | US | disclosed |
| US-9497979-B2 | Multi-region chewing gum composition including isomalt gum region | INTERCONTINENTAL GREAT BRANDS LLC (US) | 2016-11-22 | — | — | US | disclosed |
| US-20110159142-A1 | SUGAR FREE CONFECTIONERY; METHODS OF MAKING SAME; AND USE IN PREPARING MULTILAYERED CONFECTIONERY | INTERCONTINENTAL GREAT BRANDS LLC | 2011-06-30 | — | — | US | disclosed |
| US-20110159143-A1 | MULTILAYERED SUGAR FREE MANNITOL CONFECTIONERY AND METHODS OF MAKING SAME | INTERCONTINENTAL GREAT BRANDS LLC | 2011-06-30 | — | — | US | disclosed |
| US-20110129563-A1 | MULTI-REGION CONFECTIONERY | CADBURY ADAMS USA LLC (US) | 2011-06-02 | — | — | US | disclosed |
| US-7893072-B2 | Cool-genic compounds as anticarcinogenic agents promoting apoptosis and inhibit angiogenesis; antiproliferative agents | GENENTECH, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-7893072-B2 | Cool-genic compounds as anticarcinogenic agents promoting apoptosis and inhibit angiogenesis; antiproliferative agents | GENENTECH, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-20090142443-A1 | MULTI-REGION CHEWING GUM WITH ACTIVES | CADBURY ADAMS USA LLC (US) | 2009-06-04 | — | — | US | disclosed |
| US-20090028998-A1 | MULTI-REGION CHEWING GUM COMPOSITION INCLUDING SATURATED PARTICULATE POLYOLS | CADBURY ADAMS USA LLC (US) | 2009-01-29 | — | — | US | disclosed |
| US-20080248089-A1 | EDIBLE PRODUCTS FOR THE TREATMENT OF NASAL PASSAGES | CADBURY ADAMS USA LLC (US) | 2008-10-09 | — | — | US | disclosed |
| US-20080014302-A1 | MULTI-REGION CHEWING GUM COMPOSITION INCLUDING ISOMALT GUM REGION | CADBURY ADAMS USA LLC (US) | 2008-01-17 | — | — | US | disclosed |
| US-20070221236-A1 | Cooling compositions including menthyl esters | CADBURY ADAMS USA LLC. | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080248089-A1 | EDIBLE PRODUCTS FOR THE TREATMENT OF NASAL PASSAGES | TAS2R40, TAS2R3, TAS2R4 | TRPM8 206/4885EPHX1 4108/4885MAPT 1938/4885 |
| US-10278408-B2 | Transparent and transluscent liquid filled candy; process of making thereof; sugar-free liquid edible composition; and use thereof | AGL, CEL, LIPA | TRPM8 4281/4885EPHX1 3161/4885MAPT 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.