SCHEMBL4143582

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4579012	0.94	IL6 (0.73)	IL6HTR2CL3MBTL1ALDH1A1MAPT
	SCHEMBL4127299	0.93	IL6 (0.82)	IL6HTR2CL3MBTL1MAPTKMT2A
	SCHEMBL4135691	0.92	IL6 (0.71)	IL6HTR2CL3MBTL1ALDH1A1FFAR1
	SCHEMBL4579362	0.92	IL6 (0.71)	IL6HTR2CL3MBTL1ALDH1A1FFAR1
	SCHEMBL4580376	0.90	IL6 (0.69)	IL6HTR2CL3MBTL1ALDH1A1MAPK14
	SCHEMBL16556485	0.90	IL6 (0.69)	IL6HTR2CL3MBTL1ALDH1A1MAPT
	SCHEMBL4581165	0.90	IL6 (0.69)	IL6HTR2CL3MBTL1FFAR1FFAR4
	SCHEMBL4579573	0.90	IL6 (0.69)	IL6HTR2CL3MBTL1FFAR1FFAR4
	SCHEMBL4127403	0.90	IL6 (0.69)	IL6HTR2CL3MBTL1ALDH1A1MAPT
	SCHEMBL4581924	0.90	IL6 (0.75)	IL6L3MBTL1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.