SCHEMBL4143586

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4579844	0.93	IL6 (0.90)	IL6FFAR1FFAR4BACE1MEN1
	SCHEMBL4581788	0.91	IL6 (1.00)	IL6FFAR1FFAR4BACE1MEN1
	SCHEMBL4580952	0.90	IL6 (0.86)	IL6FFAR1FFAR4BACE1MEN1
	SCHEMBL4581342	0.89	IL6 (0.84)	IL6BACE1MDM2MEN1KMT2A
	SCHEMBL4134613	0.89	IL6 (0.84)	IL6FFAR1FFAR4MEN1KMT2A
	SCHEMBL4126541	0.89	IL6 (0.83)	IL6TP53MDM2HTR2C
	SCHEMBL4135144	0.89	IL6 (0.83)	IL6FFAR1FFAR4BACE1MEN1
	SCHEMBL4127299	0.88	IL6 (0.82)	IL6FFAR1FFAR4MEN1KMT2A
	SCHEMBL4581503	0.88	IL6 (0.82)	IL6FFAR1FFAR4
	SCHEMBL4144125	0.88	IL6 (0.82)	IL6FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.