Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480191 | 0.81 | MAPK1 (0.33) | MAPK1HPSE | |
| SCHEMBL1366378 | 0.81 | PKM (0.36) | SLC1A2MEN1KMT2AGRIK2ALDH1A1 | |
| SCHEMBL17756064 | 0.75 | SLC1A2 (0.58) | SLC1A2MEN1KMT2ABLMSLC1A1 | |
| SCHEMBL3427826 | 0.75 | SLC1A2 (0.58) | SLC1A2MEN1KMT2ABLMSLC1A1 | |
| SCHEMBL6225233 | 0.73 | BTK (0.36) | SLC1A2MEN1KMT2AGRIK2ALDH1A1 | |
| SCHEMBL11459266 | 0.72 | ARG1 (0.37) | SLC1A2MEN1KMT2AGRIK2ALDH1A1 | |
| SCHEMBL2177343 | 0.72 | MEN1 (0.61) | SLC1A2MEN1KMT2ABLM | |
| SCHEMBL17756096 | 0.72 | MEN1 (0.61) | SLC1A2MEN1KMT2ABLM | |
| SCHEMBL630081 | 0.71 | SLC1A2 (0.49) | SLC1A2MEN1KMT2ABLM | |
| SCHEMBL12909511 | 0.71 | MAPK1 (0.39) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074569-A1 | TARGETING AND THERAPEUTIC COMPOUNDS WITH A POLYPROLINE-COMPRISING SPACER AND GAS-FILLED MICROVESICLES COMPRISING SAID COMPOUNDS | BRACCO INTERNATIONAL BV (NL) | 2009-06-18 | — | — | WO | disclosed |