SCHEMBL4144579

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4144584	1.00	PIM1 (0.40)	PIM1CYP19A1NQO2KDRALDH1A1
	SCHEMBL4144222	0.90	NPC1 (0.44)	ALDH1A1KDM4ENPC1PKMRAB9A
	SCHEMBL4136045	0.90	TUBB4A (0.38)	NQO2KDRCHEK1CCNA2CDK2
	SCHEMBL4144227	0.90	NPC1 (0.44)	ALDH1A1KDM4ENPC1PKMRAB9A
	SCHEMBL4136051	0.90	TUBB4A (0.38)	NQO2KDRCHEK1CCNA2CDK2
	SCHEMBL4145366	0.90	KDR (0.44)	KDRCHEK1LCKFGFR1CDK4
	SCHEMBL4145369	0.90	KDR (0.44)	KDRCHEK1LCKFGFR1CDK4
	SCHEMBL4137389	0.89	NFE2L2 (0.38)	NQO2KDRALDH1A1CHEK1FGFR1
	SCHEMBL4137527	0.89	KDR (0.39)	KDRALDH1A1CHEK1CCNA2CDK2
	SCHEMBL4137384	0.89	NFE2L2 (0.38)	NQO2KDRALDH1A1CHEK1FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.