Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 1/20 | 0.70 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.58 |
| ▸ | CHRNG | P07510 | 2/20 | 0.58 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.58 |
| ▸ | CHRND | Q07001 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.56 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819237 | 1.00 | MDM4 (0.70) | MDM4MDM2TSHRATMCHRNA1 | |
| SCHEMBL4144661 | 1.00 | MDM4 (0.70) | MDM4MDM2TSHRATMCHRNA1 | |
| SCHEMBL4164846 | 1.00 | MDM4 (0.70) | MDM4MDM2TSHRATMCHRNA1 | |
| SCHEMBL4157633 | 0.94 | MDM4 (0.64) | MDM4MDM2TSHRALDH1A1KMT2A | |
| SCHEMBL13819236 | 0.94 | MDM4 (0.64) | MDM4MDM2TSHRALDH1A1KMT2A | |
| SCHEMBL4156603 | 0.93 | ATM (0.65) | MDM4MDM2ATMALDH1A1MEN1 | |
| SCHEMBL4156601 | 0.93 | ATM (0.65) | MDM4MDM2ATMALDH1A1MEN1 | |
| SCHEMBL13588075 | 0.91 | MDM4 (0.63) | MDM4MDM2TSHRATMCHRNA1 | |
| SCHEMBL10745859 | 0.91 | TSHR (0.62) | MDM4MDM2TSHRCHRNA1CHRNG | |
| SCHEMBL3927422 | 0.90 | MDM4 (0.57) | MDM4MDM2TSHRCHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384495-B | Novel modulators of metabotropic and ion-channel transmembrane receptors and uses thereof | IBD治疗学有限责任公司 | 2023-07-18 | — | — | CN | claimed |
| EP-3792247-A1 | NOVEL MODULATOR OF METABOTROPIC AND IONOTROPIC TRANSMEMBRANE RECEPTORS AND USE THEREOF | IBD Therapeutics LLC (RU) | 2021-03-17 | — | — | EP | claimed |
| US-20210070692-A1 | NOVEL MODULATOR OF METABOTROPIC AND IONOTROPIC TRANSMEMBRANE RECEPTORS AND USE THEREOF | IBD THERAPEUTICS LLC (RU) | 2021-03-11 | — | — | US | claimed |
| CN-112384495-A | Novel modulators of metabolic and ion channel transmembrane receptors and uses thereof | IBD治疗学有限责任公司 | 2021-02-19 | — | — | CN | claimed |
| EP-1876169-B1 | PHENYL-CONTAINING N-ACYL AMINE AND AMINOACID DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, A PHARMACEUTICAL COMPOSITION AND THE USE THEREOF | OBSCHESTVO S OGRANICHENNOI OTVETSTENNOSTIYU PHARMENTPR (RU) | 2015-12-30 | — | — | EP | claimed |
| US-8309766-B2 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | Obschestvo S. Organichennoi Otvetstvennostiyu Pharmenterprises (RU) | 2012-11-13 | — | — | US | claimed |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2009-04-30 | — | — | US | claimed |
| EP-1876169-A1 | PHENYL-CONTAINING N-ACYL AMINE AND AMINOACID DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, A PHARMACEUTICAL COMPOSITION AND THE USE THEREOF | Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) | 2008-01-09 | — | — | EP | claimed |
| CN-112384495-B | Novel modulators of metabotropic and ion-channel transmembrane receptors and uses thereof | IBD治疗学有限责任公司 | 2023-07-18 | — | — | CN | disclosed |
| US-11414377-B2 | Modulator of metabotropic and ionotropic transmembrane receptors and use thereof | IBD THERAPEUTICS LLC (RU) | 2022-08-16 | — | — | US | disclosed |
| EP-3792247-A1 | NOVEL MODULATOR OF METABOTROPIC AND IONOTROPIC TRANSMEMBRANE RECEPTORS AND USE THEREOF | IBD Therapeutics LLC (RU) | 2021-03-17 | — | — | EP | disclosed |
| US-20210070692-A1 | NOVEL MODULATOR OF METABOTROPIC AND IONOTROPIC TRANSMEMBRANE RECEPTORS AND USE THEREOF | IBD THERAPEUTICS LLC (RU) | 2021-03-11 | — | — | US | disclosed |
| EP-1876169-B1 | PHENYL-CONTAINING N-ACYL AMINE AND AMINOACID DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, A PHARMACEUTICAL COMPOSITION AND THE USE THEREOF | OBSCHESTVO S OGRANICHENNOI OTVETSTENNOSTIYU PHARMENTPR (RU) | 2015-12-30 | — | — | EP | disclosed |
| US-8309766-B2 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | Obschestvo S. Organichennoi Otvetstvennostiyu Pharmenterprises (RU) | 2012-11-13 | — | — | US | disclosed |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11414377-B2 | Modulator of metabotropic and ionotropic transmembrane receptors and use thereof | TRPM8, TRPV1, TRPA1 | MDM4 4294/4885MDM2 3187/4885TSHR 951/4885 |
| US-20210070692-A1 | NOVEL MODULATOR OF METABOTROPIC AND IONOTROPIC TRANSMEMBRANE RECEPTORS AND USE THEREOF | TRPM8, TRPV1, TRPA1 | MDM4 4354/4885MDM2 3258/4885TSHR 1065/4885 |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | PAH, MAOA, APEH | MDM4 4681/4885MDM2 4424/4885TSHR 3914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.