Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.48 |
| ▸ | CTSK | P43235 | 9/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133368 | 0.86 | CTSK (0.55) | CTSSCTSKCTSL | |
| SCHEMBL4145290 | 0.84 | CTSS (0.59) | CTSSCTSKCTSL | |
| SCHEMBL4129807 | 0.83 | CTSS (0.51) | CTSSCTSKDRD2CTSL | |
| SCHEMBL4142694 | 0.83 | CTSK (0.66) | CTSSCTSKCTSL | |
| SCHEMBL4142474 | 0.83 | CTSK (0.51) | CTSSCTSKDRD2KDM4E | |
| SCHEMBL4141258 | 0.82 | CTSS (0.53) | CTSSCTSKDRD2CTSL | |
| SCHEMBL4137153 | 0.81 | CTSK (0.46) | CTSSCTSKDRD2KDM4E | |
| SCHEMBL4141659 | 0.77 | CTSK (0.64) | CTSSCTSKCTSL | |
| SCHEMBL4141268 | 0.74 | CTSS (0.57) | CTSSCTSKCTSLKDM4E | |
| SCHEMBL4133363 | 0.74 | CTSS (0.66) | CTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054467-A1 | Pyrrolo Pyrimidines as Agents for the Inhibition of Cystein Proteases | BETSCHART CLAUDIA | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054467-A1 | Pyrrolo Pyrimidines as Agents for the Inhibition of Cystein Proteases | CTSK, CTSS, CTSZ | CTSS 2/4885CTSK 1/4885DRD2 4870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.