SCHEMBL4145479

SCHEMBL4145479

CC1(C)COP(=O)(Oc2ccc(-c3ccccc3)cc2)OC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.37
MAPK1 P28482 1/20 0.37
NPC1 O15118 4/20 0.36
RAB9A P51151 3/20 0.36
CYP1A2 P05177 2/20 0.35
GAA P10253 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
PKM P14618 1/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3674965 0.90 MAPK1 (0.44) HSD17B10MAPK1NPC1CYP1A2GAA
SCHEMBL21096821 0.87 CA1 (0.36) HSD17B10MAPK1NPC1RAB9ACYP1A2
SCHEMBL13697355 0.87 EPHX1 (0.37) HSD17B10MAPK1PTGER4
SCHEMBL28060705 0.83 CYP1A2 (0.36) HSD17B10MAPK1NPC1RAB9ACYP1A2
SCHEMBL8761873 0.82 CYP3A4 (0.46) HSD17B10MAPK1CYP1A2GAACYP2C9
SCHEMBL25014156 0.81 PPARG (0.33) NPC1RAB9ACA1CA2CA9
SCHEMBL13697353 0.80 ALDH1A1 (0.42) HSD17B10MAPK1CYP1A2KMT2AMEN1
SCHEMBL4140078 0.79 POLB (0.35) MAPK1RAB9AGAATDP1SMN1; SMN2
SCHEMBL8745424 0.79 MAPK1 (0.33) HSD17B10MAPK1CYP1A2GAACYP2C9
SCHEMBL12669990 0.76 RECQL (0.41) HSD17B10MAPK1CYP2C19KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10584251-B2 Flame retardant coating agent for vehicle seat, and manufacturing method for flame retardant vehicle seat material NICCA CHEMICAL CO., LTD. (JP) 2020-03-10 US disclosed
US-10577509-B2 Flame retardant coating agent for vehicle seat, and manufacturing method for flame retardant vehicle seat material NICCA CHEMICAL CO., LTD. (JP) 2020-03-03 US disclosed
US-20180273771-A1 FLAME RETARDANT COATING AGENT FOR VEHICLE SEAT, AND MANUFACTURING METHOD FOR FLAME RETARDANT VEHICLE SEAT MATERIAL NICCA CHEMICAL CO., LTD. (JP) 2018-09-27 US disclosed
US-20160333193-A1 FLAME RETARDANT COATING AGENT FOR VEHICLE SEAT, AND MANUFACTURING METHOD FOR FLAME RETARDANT VEHICLE SEAT MATERIAL NICCA CHEMICAL CO., LTD. (JP) 2016-11-17 US disclosed
CN-105829466-A Flame-retardant coating agent for vehicle seat and method for producing flame-retardant vehicle seat material 日华化学株式会社 2016-08-03 CN disclosed
US-8835541-B2 Phosphorus compounds, use thereof and flame retarding polyester fibers DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2014-09-16 US disclosed
US-8835541-B2 Phosphorus compounds, use thereof and flame retarding polyester fibers DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2014-09-16 US disclosed
US-8835541-B2 Phosphorus compounds, use thereof and flame retarding polyester fibers DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2014-09-16 US disclosed
EP-1925622-B1 PHOSPHORUS COMPOUND, USE THEREOF AND FLAME-RETARDANT POLYESTER FIBER DAIHACHI CHEM IND (JP) 2013-10-16 EP disclosed
EP-1925622-B1 PHOSPHORUS COMPOUND, USE THEREOF AND FLAME-RETARDANT POLYESTER FIBER DAIHACHI CHEM IND (JP) 2013-10-16 EP disclosed
US-20090227713-A1 PHOSPHORUS COMPOUNDS, USE THEREOF AND FLAME RETARDING POLYESTER FIBERS DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2009-09-10 US disclosed
US-20090227713-A1 PHOSPHORUS COMPOUNDS, USE THEREOF AND FLAME RETARDING POLYESTER FIBERS DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2009-09-10 US disclosed
US-20090227713-A1 PHOSPHORUS COMPOUNDS, USE THEREOF AND FLAME RETARDING POLYESTER FIBERS DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2009-09-10 US disclosed
EP-1925622-A1 PHOSPHORUS COMPOUND, USE THEREOF AND FLAME-RETARDANT POLYESTER FIBER DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2008-05-28 EP disclosed
EP-1925622-A1 PHOSPHORUS COMPOUND, USE THEREOF AND FLAME-RETARDANT POLYESTER FIBER DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2008-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227713-A1 PHOSPHORUS COMPOUNDS, USE THEREOF AND FLAME RETARDING POLYESTER FIBERS POLL, FGFR1, FGFR4 HSD17B10 1852/4885MAPK1 1155/4885NPC1 4185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.