Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.42 |
| ▸ | CETP | P11597 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1630183 | 0.85 | SPHK1 (0.52) | LMNASPHK1SPHK2CETPCYP2D6 | |
| SCHEMBL18249947 | 0.83 | LMNA (0.44) | LMNASPHK1SPHK2CETPTSHR | |
| SCHEMBL21428085 | 0.83 | SPHK1 (0.55) | LMNASPHK1SPHK2CETPCYP2D6 | |
| SCHEMBL21636787 | 0.83 | SPHK1 (0.55) | LMNASPHK1SPHK2CETPCYP2D6 | |
| SCHEMBL15057401 | 0.83 | SPHK1 (0.55) | LMNASPHK1SPHK2CETPCYP2D6 | |
| Hydrochloric Acid SCHEMBL7612591 | 0.81 | SPHK1 (0.53) | LMNASPHK1SPHK2CETPCYP2D6 | |
| SCHEMBL28056561 | 0.81 | LMNA (0.43) | LMNASPHK1SPHK2CETPTSHR | |
| SCHEMBL25058928 | 0.80 | SPHK2 (0.40) | LMNASPHK1SPHK2CETPTSHR | |
| SCHEMBL15750870 | 0.79 | LMNA (0.40) | LMNASPHK1SPHK2CETPTSHR | |
| SCHEMBL11213426 | 0.73 | SPHK2 (0.35) | SPHK1SPHK2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372207-A1 | CARBONATED AEROSOL EXTERNAL PREPARATION FOR SKIN | KAO CORPORATION (JP) | 2023-11-23 | — | — | US | disclosed |
| US-20230372207-A1 | CARBONATED AEROSOL EXTERNAL PREPARATION FOR SKIN | KAO CORPORATION (JP) | 2023-11-23 | — | — | US | disclosed |
| US-11730686-B2 | Cosmetic skincare compositions | THE BOOTS COMPANY PLC (GB) | 2023-08-22 | — | — | US | disclosed |
| US-11730686-B2 | Cosmetic skincare compositions | THE BOOTS COMPANY PLC (GB) | 2023-08-22 | — | — | US | disclosed |
| WO-2022071574-A1 | CARBONATED AEROSOL FOR TOPICAL USE | 花王株式会社 | 2022-04-07 | — | — | WO | disclosed |
| WO-2020250966-A1 | EMULSION COMPOSITION | 花王株式会社 | 2020-12-17 | — | — | WO | disclosed |
| US-9694076-B2 | Vesicle composition | KAO CORPORATION (JP) | 2017-07-04 | — | — | US | disclosed |
| US-9694076-B2 | Vesicle composition | KAO CORPORATION (JP) | 2017-07-04 | — | — | US | disclosed |
| CN-106317369-A | Aqueous polyurethane resin dispersion and use thereof | 宇部兴产株式会社 | 2017-01-11 | — | — | CN | disclosed |
| US-20160166698-A1 | VESICLE COMPOSITION | KAO CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-8178584-B2 | Sphingosines, fatty acid, and oil; improved stability and feel to skin | KAO CORPORATION (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178584-B2 | Sphingosines, fatty acid, and oil; improved stability and feel to skin | KAO CORPORATION (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20120108661-A1 | EMULSIFIED COMPOSITION | KAO CORPORATION (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20120108661-A1 | EMULSIFIED COMPOSITION | KAO CORPORATION (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20110263714-A1 | Reverse Vesicle | KAO CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
| US-20110263714-A1 | Reverse Vesicle | KAO CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
| US-20100311836-A1 | OIL-IN-WATER EMULSIFIED COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20100311836-A1 | OIL-IN-WATER EMULSIFIED COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
| US-7846969-B2 | Ceramide emulsions | KAO CORPORATION (JP) | 2010-12-07 | — | — | US | disclosed |
| US-7846969-B2 | Ceramide emulsions | KAO CORPORATION (JP) | 2010-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372207-A1 | CARBONATED AEROSOL EXTERNAL PREPARATION FOR SKIN | CERT1, CERS2, SGMS2 | LMNA 390/4885SPHK1 25/4885SPHK2 30/4885 |
| US-20160166698-A1 | VESICLE COMPOSITION | SGMS1, EXOSC10, SGMS2 | LMNA 3672/4885SPHK1 56/4885SPHK2 90/4885 |
| US-20100311836-A1 | OIL-IN-WATER EMULSIFIED COSMETIC COMPOSITION | CERT1, SGMS1, DEGS1 | LMNA 600/4885SPHK1 17/4885SPHK2 31/4885 |
| US-20120108661-A1 | EMULSIFIED COMPOSITION | CERT1, S1PR4, S1PR3 | LMNA 1152/4885SPHK1 15/4885SPHK2 19/4885 |
| US-20110263714-A1 | Reverse Vesicle | SGMS1, EXOSC10, SGMS2 | LMNA 380/4885SPHK1 63/4885SPHK2 108/4885 |
| US-11730686-B2 | Cosmetic skincare compositions | SPHK1, SPHK2, S1PR2 | LMNA 1281/4885SPHK1 1/4885SPHK2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.