SCHEMBL414559

SCHEMBL414559

CCCc1c(N)ccc(S(N)(=O)=O)c1CCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 15/20 0.43
CA1 P00915 10/20 0.39
CA12 O43570 9/20 0.39
CA9 Q16790 7/20 0.39
CA7 P43166 7/20 0.39
CA14 Q9ULX7 4/20 0.39
CA6 P23280 4/20 0.39
CA4 P22748 3/20 0.39
CA5A P35218 3/20 0.39
CA5B Q9Y2D0 3/20 0.39
CYP2C9 P11712 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 1/20 0.34
PKM P14618 2/20 0.33
PDIA6 Q15084 1/20 0.33
NOS2 P35228 1/20 0.33
CA13 Q8N1Q1 2/20 0.33
TSHR P16473 1/20 0.33
CA3 P07451 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8198872 0.81 CA2 (0.43) CA2CA1CA12CA9CA7
SCHEMBL10954398 0.81 CA2 (0.42) CA2CA1CA12CA9CA7
Hydrochloric Acid SCHEMBL28285726 0.80 PKM (0.38) CA2CA1CA12CA9CA7
SCHEMBL458150 0.79 NOS2 (0.45) CA2CYP2C9SMN1; SMN2KDM4EALDH1A1
SCHEMBL5505278 0.77 CA2 (0.45) CA2CA1CA12CA9CA7
SCHEMBL5507157 0.76 CA2 (0.46) CA2CA1CA12CA9CA7
SCHEMBL27420115 0.76 CISD1 (0.42) CA2CA1CA12CA9CA7
SCHEMBL28204304 0.75 TDP1 (0.41) CA2CA1CA12CA9CA7
SCHEMBL28043732 0.74 CA2 (0.39) CA2CA1CA12CA9CA7
SCHEMBL2724413 0.74 CA2 (0.48) CA2CA1CA12CA9CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142804-B2 Pest control sheet MAKHTESHIM CHEMICAL WORKS LTD. (IL) 2012-03-27 US claimed
EP-0257771-A1 Herbicidal method using diflufenican RHONE-POULENC AGRICULTURE LTD. (GB) 1988-03-02 EP claimed
US-12543674-B2 Embryogenesis factors for cellular reprogramming of a plant cell PIONEER HI-BRED INTERNATIONAL, INC. (US) 2026-02-10 US disclosed
US-20250277230-A1 PARTHENOGENESIS METHODS AND COMPOSITIONS PIONEER HI-BRED INTERNATONAL, INC. (US) 2025-09-04 US disclosed
US-20250115924-A1 SYSTEMS AND METHODS FOR CELLULAR REPROGRAMMING OF A PLANT CELL PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-04-10 US disclosed
US-20250115927-A1 METHODS FOR CLONAL PLANT PRODUCTION PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-04-10 US disclosed
US-20250101453-A1 METHODS OF PARTHENOGENIC HAPLOID INDUCTION AND HAPLOID CHROMOSOME DOUBLING PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-03-27 US disclosed
US-12146147-B2 Methods for clonal plant production PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-11-19 US disclosed
US-20240002877-A1 PARTHENOGENESIS FACTORS AND METHODS OF USING SAME PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-01-04 US disclosed
US-20230407324-A1 DOUBLED HAPLOID INDUCER PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-12-21 US disclosed
US-20230203516-A1 SYSTEMS AND METHODS FOR CELLULAR REPROGRAMMING OF A PLANT CELL PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-06-29 US disclosed
US-20120311736-A1 SELECTIVE ABLATION OF DIPLOID EMBRYOS E.I. du Pont de Nemours and Company and Pioneer Hi-Bred International 2012-12-06 US disclosed
US-8269061-B2 Selective ablation of diploid embryos E.I. du Pont de Nmeours and Company (US) 2012-09-18 US disclosed
US-20120023612-A1 SELECTIVE ABLATION OF DIPLOID EMBRYOS E. I. DU PONT DE NEMOURS AND COMPANY AND PIONEER HI-BRED INTERNATIONAL, INC. (US) 2012-01-26 US disclosed
US-20080216191-A1 Pollinating silks of maize ear, contacting haploid embryo with chromosome doubling agent (colchicine), propagate cells; generating homozygosity in plants PIONEER HI-BRED INTERNATIONAL, INC. (US) 2008-09-04 US disclosed
US-20080189801-A1 Selective Ablation of Diploid Embryos PIONNER HI-BRED INTERNATIONAL, INC. 2008-08-07 US disclosed
EP-0243522-B1 SYSTEMIC HERBICIDAL COMPOSITIONS AND METHODS OF USE UNION OIL COMPANY OF CALIFORNIA (US) 1989-09-13 EP disclosed
EP-0330137-A1 Intermediate compounds for the preparation of 1,2,4-triazolo [1,5-a]pyrimidine-2-sulfonamides DowElanco (US) 1989-08-30 EP disclosed
EP-0257771-A1 Herbicidal method using diflufenican RHONE-POULENC AGRICULTURE LTD. (GB) 1988-03-02 EP disclosed
EP-0020052-A1 Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds ROHM AND HAAS COMPANY (US) 1980-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12543674-B2 Embryogenesis factors for cellular reprogramming of a plant cell CCNB2, CCNB1, CCNB3 CA2 3910/4885CA1 3691/4885CA12 4001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.