Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699904 | 0.91 | PAOX (0.39) | GAAEGLN1TP53CYP2C19ALDH1A1 | |
| SCHEMBL31683981 | 0.80 | FFAR3 (0.36) | ALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL30547298 | 0.80 | EGLN1 (0.37) | EGLN1CYP2D6ALDH1A1KDM4EPOLB | |
| SCHEMBL29202503 | 0.79 | KDM4E (0.34) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL11078575 | 0.78 | — | — | |
| SCHEMBL2240590 | 0.78 | CA3 (0.42) | EGLN1TP53CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL29454886 | 0.77 | TSHR (0.39) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL19013345 | 0.76 | PAOX (0.50) | CYP2D6CYP2C19POLBPAOXCA3 | |
| SCHEMBL4774203 | 0.76 | PAOX (0.50) | CYP2D6CYP2C19POLBPAOXCA3 | |
| SCHEMBL20759820 | 0.75 | FFAR3 (0.39) | EGLN1ALDH1A1KDM4EPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150196586-A1 | POLYMERIC MOLECULAR RECEPTORS AS PHOSPHATE SEQUESTRANTS | GENZYME CORPORATION | 2015-07-16 | — | — | US | disclosed |
| US-8986669-B2 | Method for removing phosphate and polymer used therefore | GENZYME CORPORATION (US) | 2015-03-24 | — | — | US | disclosed |
| US-20090047233-A1 | Method for removing Phosphate and Polymer Used Therefore | GENZYME CORPORATION | 2009-02-19 | — | — | US | disclosed |
| EP-1951266-A2 | METHOD FOR REMOVING PHOSPHATE AND POLYMER USED THEREFORE | Genzyme Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007027566-A2 | METHOD FOR REMOVING PHOSPHATE AND POLYMER USED THEREFORE | GENZYME CORPORATION (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047233-A1 | Method for removing Phosphate and Polymer Used Therefore | PHPT1, PNKP, PHYKPL | GAA 494/4885MGAM 90/4885SI 119/4885 |
| US-20150196586-A1 | POLYMERIC MOLECULAR RECEPTORS AS PHOSPHATE SEQUESTRANTS | PHPT1, SLC34A2, SLC34A1 | GAA 1192/4885MGAM 713/4885SI 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.