⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30130697 | 0.82 | — | — | |
| SCHEMBL2605560 | 0.81 | MGAM (0.38) | — | |
| SCHEMBL3228304 | 0.80 | GAA (0.44) | — | |
| SCHEMBL6168846 | 0.79 | — | — | |
| SCHEMBL4145822 | 0.78 | GAA (0.33) | — | |
| SCHEMBL6730874 | 0.77 | — | — | |
| SCHEMBL721438 | 0.77 | — | — | |
| SCHEMBL13241894 | 0.77 | — | — | |
| SCHEMBL24135881 | 0.77 | THRB (0.35) | — | |
| SCHEMBL2606660 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022250069-A1 | SULFUR-CONTAINING PYRAZOLE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT INCLUDING SULFUR-CONTAINING PYRAZOLE COMPOUND AS ACTIVE INGREDIENT | 三井化学アグロ株式会社 | 2022-12-01 | — | — | WO | disclosed |
| CN-106061483-B | Sustained release conjugates of SN-38 | 普洛林克斯有限责任公司 | 2021-01-08 | — | — | CN | disclosed |
| EP-3052101-B1 | SLOW-RELEASE CONJUGATES OF SN-38 | PROLYNX LLC (US) | 2019-11-20 | — | — | EP | disclosed |
| US-10342792-B2 | Slow-release conjugates of SN-38 | PROLYNX LLC (US) | 2019-07-09 | — | — | US | disclosed |
| US-20180289695-A1 | SLOW-RELEASE CONJUGATES OF SN-38 | PROLYNX LLC (US) | 2018-10-11 | — | — | US | disclosed |
| US-10016411-B2 | Slow-release conjugates of SN-38 | PROLYNX LLC (US) | 2018-07-10 | — | — | US | disclosed |
| CN-106061483-A | Slow-release conjugates of SN-38 | 普洛林克斯有限责任公司 | 2016-10-26 | — | — | CN | disclosed |
| US-20160243106-A1 | SLOW-RELEASE CONJUGATES OF SN-38 | PROLYNX LLC (US) | 2016-08-25 | — | — | US | disclosed |
| EP-3052101-A1 | SLOW-RELEASE CONJUGATES OF SN-38 | Prolynx LLC (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015051307-A1 | SLOW-RELEASE CONJUGATES OF SN-38 | PROLYNX LLC (US) | 2015-04-09 | — | — | WO | disclosed |
| US-4426523-A | Preparation of 1-amino-1,3,5-triazine-2,4(1H, 3H)-diones | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-17 | — | — | US | disclosed |