Urethane

Urethane

SCHEMBL4146012

C=C(C)C(=O)OOc1ccccc1.CCOC(N)=O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
ALDH1A1 P00352 2/20 0.43
ALOX15 P16050 1/20 0.43
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
PKM P14618 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ELANE P08246 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP1 Q9NUW8 2/20 0.38
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
CRHBP P24387 1/20 0.38
RAB9A P51151 1/20 0.38
CRHR2 Q13324 1/20 0.38
TSHR P16473 1/20 0.37
LMNA P02545 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL632410 0.84 ELANE (0.50) MAPTALDH1A1ALOX15ELANEKMT2A
Ethylene Glycol SCHEMBL2979502 0.82 ELANE (0.45) MAPTALDH1A1ALOX15ELANEMEN1
Methacrylic Acid SCHEMBL2939572 0.81 ELANE (0.47) MAPTALDH1A1ALOX15ELANEKMT2A
Urethane SCHEMBL1692248 0.80 THRB (0.47) MAPTALDH1A1ALOX15CYP1A2CYP2D6
Carbamic Acid Phenyl Ester SCHEMBL3950192 0.79 MAPT (0.49) MAPTALDH1A1ELANEMEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL10437285 0.77 ELANE (0.41) MAPTALDH1A1SMN1; SMN2ELANEMEN1
Urethane SCHEMBL18795100 0.76 ALOX15 (0.58) MAPTALDH1A1ALOX15TDP1TSHR
Tetraethylene Glycol SCHEMBL10716452 0.75 ELANE (0.40) MAPTALDH1A1SMN1; SMN2ELANEMEN1
SCHEMBL16259055 0.75 ELANE (0.47) MAPTALDH1A1ALOX15ELANEKMT2A
Phenetole SCHEMBL28832428 0.74 ALDH1A1 (0.53) MAPTALDH1A1CYP1A2SMN1; SMN2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1994432-A4 FLAME RETARDANT RETROREFLECTIVE FILM STRUCTURE REFLEXITE CORP (US) 2009-06-24 EP disclosed
US-7503664-B2 Flame retardant retroreflective film structure REFLEXITE CORPORATION (US) 2009-03-17 US disclosed
EP-1994432-A2 FLAME RETARDANT RETROREFLECTIVE FILM STRUCTURE Reflexite Corporation (US) 2008-11-26 EP disclosed
WO-2007108971-A2 FLAME RETARDANT RETROREFLECTIVE FILM STRUCTURE REFLEXITE CORPORATION (US) 2007-09-27 WO disclosed
US-20070223092-A1 Flame retardant retroreflective film structure ORAFOL AMERICAS INC. 2007-09-27 US disclosed