Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PLEC | Q15149 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145291 | 0.84 | POLB (0.44) | CNR1CNR2ALDH1A1TP53POLB | |
| SCHEMBL4149731 | 0.83 | TP53 (0.36) | CNR1CNR2PLECTP53POLB | |
| SCHEMBL4147214 | 0.80 | PARP1 (0.40) | CNR1CNR2PLECBCHEACHE | |
| SCHEMBL4146312 | 0.78 | CNR1 (0.46) | CNR1CNR2TP53SMN1; SMN2MAPT | |
| SCHEMBL13808013 | 0.78 | CNR1 (0.60) | CNR1CNR2PLECALDH1A1TP53 | |
| SCHEMBL4668629 | 0.76 | PLEC (0.49) | CNR1CNR2PLECALDH1A1TP53 | |
| SCHEMBL4884821 | 0.75 | CNR1 (0.59) | CNR1CNR2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL13808012 | 0.72 | CNR1 (0.63) | CNR1CNR2PLECTP53POLB | |
| SCHEMBL13808014 | 0.72 | CNR1 (0.62) | CNR1CNR2PLECALDH1A1TP53 | |
| SCHEMBL14206283 | 0.72 | CNR1 (0.52) | CNR1CNR2PLECTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009075691-A1 | CB-1 MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2009-06-18 | — | — | WO | disclosed |