Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PLEC | Q15149 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146318 | 0.83 | CNR1 (0.35) | TP53SMN1; SMN2PLECNPSR1MAPT | |
| SCHEMBL4149729 | 0.82 | TP53 (0.47) | TP53SMN1; SMN2NPSR1PLA2G1BMAPT | |
| SCHEMBL4669465 | 0.77 | TP53 (0.59) | TP53SMN1; SMN2PLECNPSR1PLA2G1B | |
| SCHEMBL4145291 | 0.67 | POLB (0.44) | TP53SMN1; SMN2NPSR1MAPTCNR1 | |
| SCHEMBL4668629 | 0.67 | PLEC (0.49) | TP53SMN1; SMN2PLECNPSR1MAPT | |
| SCHEMBL4146312 | 0.65 | CNR1 (0.46) | TP53SMN1; SMN2NPSR1MAPTCNR1 | |
| SCHEMBL13808013 | 0.64 | CNR1 (0.60) | TP53SMN1; SMN2PLECNPSR1MAPT | |
| SCHEMBL14043890 | 0.64 | CNR1 (0.48) | TP53SMN1; SMN2PLECNPSR1MAPT | |
| SCHEMBL13808006 | 0.64 | PLEC (0.46) | TP53SMN1; SMN2PLECNPSR1MAPT | |
| SCHEMBL13808004 | 0.64 | CNR1 (0.49) | TP53SMN1; SMN2PLECNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009075691-A1 | CB-1 MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2009-06-18 | — | — | WO | disclosed |