SCHEMBL4147579

SCHEMBL4147579

CCC=C(C(C)=O)C(=O)OCC

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 2/20 0.69
NPSR1 Q6W5P4 3/20 0.52
ALDH1A1 P00352 6/20 0.46
CYP2D6 P10635 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 7/20 0.44
KMT2A Q03164 7/20 0.44
GAA P10253 3/20 0.44
LMNA P02545 4/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPT P10636 9/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
MAPK1 P28482 2/20 0.41
CYP2C9 P11712 1/20 0.41
S1PR4 O95977 1/20 0.41
S1PR1 P21453 1/20 0.41
KDM4E B2RXH2 2/20 0.40
HSP90AA1 P07900 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4147576 1.00 GLO1 (0.69) GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL1939600 0.89 NPSR1 (0.58) GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL13269641 0.89 NPSR1 (0.58) GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL11719302 0.84 GLO1 (0.60) GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL11719294 0.84 GLO1 (0.60) GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL14341409 0.83 GLO1 (0.53) GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL11718849 0.83 GLO1 (0.64) GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL11718842 0.83 GLO1 (0.64) GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL11378098 0.82 GLO1 (0.75) GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL9278827 0.82 GLO1 (0.75) GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105126910-B A kind of C2Symmetry imidazolylphenyl rare-earth metal catalyst, preparation method and application 北京理工大学 2019-01-22 CN claimed
CN-109071912-A Thermoplastic resin composition, method for preparing the same, and molded article comprising the same 株式会社LG化学 2018-12-21 CN claimed
CN-207224759-U fluorine modified silicon-containing release film 东莞市鼎力薄膜科技有限公司 2018-04-13 CN claimed
CN-105602484-A Transfer printing film special for ceramics and preparation method of transfer printing film DONGGUAN ZHUOYI PRINTING PRODUCT CO LTD 2016-05-25 CN claimed
CN-103804615-A Polar diene polymer and preparation method thereof CHINA PETROLEUM & CHEMICAL 2014-05-21 CN claimed
CN-103764700-A Acrylonitrile-acrylate-styrene graft copolymer and thermoplastic resin composition including same LG CHEMICAL LTD 2014-04-30 CN claimed
CN-103588939-A Polystyrene-polyacrylate block copolymer, method of manufacture thereof and article ROHM & HAAS ELECT MAT 2014-02-19 CN claimed
CN-103443147-A Method for preparing acrylic copolymer resin for optical film and method for fabricating optical film using the same LG CHEMICAL LTD 2013-12-11 CN claimed
CN-103403090-A Resin composition and optical film formed by using the same LG CHEMICAL LTD 2013-11-20 CN claimed
CN-103198877-A Light-sensing silver-coated copper electrode slurry capable of sintering in air and preparation method thereof UNIV SOUTHEAST 2013-07-10 CN claimed
CN-101072803-B Transparent copolymer resin, preparation method thereof and resin mixture composition containing transparent copolymer resin LG CHEMICAL LTD 2010-06-16 CN claimed
US-20080305066-A1 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour GIVAUDAN SA (CH) 2008-12-11 US claimed
CN-101282706-A Copolymers for cosmetic applications BASF SE (DE) 2008-10-08 CN claimed
CN-101072803-A Method for preparing transparent copolymer resin, transparent copolymer resin prepared by the method, and resin mixture composition comprising the transparent copolymer resin LG CHEMICAL LTD (KR) 2007-11-14 CN claimed
EP-1838278-A1 2-C-SUBSTITUTED PROPANE-1,3-DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR Givaudan SA (CH) 2007-10-03 EP claimed
CN-1995077-A Hydrophobic transparent acrylate copolymer and its uses SUZHOU LIULIUMING INTRAOCULAR (CN) 2007-07-11 CN claimed
CN-1989636-A Thermoplastic separator for alkaline electrochemical cells and method of making same EVEREADY BATTERY INC (US) 2007-06-27 CN claimed
CN-1965383-A Foamable element for mutually coupling of multiple components of a lamp, and lamp assembly KONINKL PHILIPS ELECTRONICS NV (NL) 2007-05-16 CN claimed
WO-2006076821-A1 2 -C-SUBSTITUTED PROPANE-1, 3 -DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR GIVAUDAN SA (CH) 2006-07-27 WO claimed
CN-1682699-A Colon soluble and intestine soluble hollow hard capsule and producing process QIANGJI PHARMACEUTICAL FACTORY (CN) 2005-10-19 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080305066-A1 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour TYR, MAL2, ACMSD GLO1 171/4885NPSR1 4097/4885ALDH1A1 152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.