Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4147579 | 1.00 | GLO1 (0.69) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL1939600 | 0.89 | NPSR1 (0.58) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL13269641 | 0.89 | NPSR1 (0.58) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL11719302 | 0.84 | GLO1 (0.60) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL11719294 | 0.84 | GLO1 (0.60) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL14341409 | 0.83 | GLO1 (0.53) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL11718849 | 0.83 | GLO1 (0.64) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL11718842 | 0.83 | GLO1 (0.64) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL11378098 | 0.82 | GLO1 (0.75) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL9278827 | 0.82 | GLO1 (0.75) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080305066-A1 | 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour | GIVAUDAN SA (CH) | 2008-12-11 | — | — | US | claimed |
| EP-1838278-A1 | 2-C-SUBSTITUTED PROPANE-1,3-DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR | Givaudan SA (CH) | 2007-10-03 | — | — | EP | claimed |
| WO-2006076821-A1 | 2 -C-SUBSTITUTED PROPANE-1, 3 -DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR | GIVAUDAN SA (CH) | 2006-07-27 | — | — | WO | claimed |
| US-20240041752-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2024-02-08 | — | — | US | disclosed |
| EP-4288022-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan SA (CH) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167123-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2022-08-11 | — | — | WO | disclosed |
| EP-4039244-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan SA (CH) | 2022-08-10 | — | — | EP | disclosed |
| US-20090137557-A1 | Calcilytic Compounds | SMITHKLINE BEECHAM CORPORATION | 2009-05-28 | — | — | US | disclosed |
| US-20080305066-A1 | 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour | GIVAUDAN SA (CH) | 2008-12-11 | — | — | US | disclosed |
| EP-1951244-A2 | CALCILYTIC COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1838278-A1 | 2-C-SUBSTITUTED PROPANE-1,3-DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR | Givaudan SA (CH) | 2007-10-03 | — | — | EP | disclosed |
| WO-2007062370-A2 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2006076821-A1 | 2 -C-SUBSTITUTED PROPANE-1, 3 -DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR | GIVAUDAN SA (CH) | 2006-07-27 | — | — | WO | disclosed |
| US-5298619-A | Platelet activating factor, antiinflammatory agents, allergens and for immunodeficient syndromes | ALTER, S.A. (ES) | 1994-03-29 | — | — | US | disclosed |
| EP-0531598-A1 | 1,4-Dihydropyridines with paf-antagonistic activity | ALTER, S.A. (ES) | 1993-03-17 | — | — | EP | disclosed |
| US-4025537-A | Preparation of 3-carboalkoxy or 3-alkanoyl furans | KRETCHMER RICHARD ALLAN | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305066-A1 | 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour | TYR, MAL2, ACMSD | GLO1 171/4885NPSR1 4097/4885ALDH1A1 152/4885 |
| US-20240041752-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | AOX1, TYR, OCIAD1 | GLO1 36/4885NPSR1 3248/4885ALDH1A1 116/4885 |
| US-20090137557-A1 | Calcilytic Compounds | CALCR, SOST, CALCB | GLO1 3290/4885NPSR1 920/4885ALDH1A1 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.