SCHEMBL414803

SCHEMBL414803

CCCCC#CC#CCCCC(=O)O

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 6/20 0.85
PTPN7 P35236 5/20 0.85
TDP1 Q9NUW8 4/20 0.66
ALDH1A1 P00352 3/20 0.66
RECQL P46063 2/20 0.66
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
KDM4E B2RXH2 1/20 0.66
USP2 O75604 1/20 0.66
POLB P06746 1/20 0.66
MAPT P10636 1/20 0.66
HPGD P15428 1/20 0.66
ALOX12 P18054 1/20 0.66
BLM P54132 1/20 0.66
MCL1 Q07820 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.66
AKR1B1 P15121 1/20 0.56
PPARG P37231 4/20 0.54
PPARD Q03181 4/20 0.54
PPARA Q07869 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL413076 0.92 PTPN7 (1.00) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL589727 0.92 PTPN7 (1.00) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL417244 0.92 PTPN7 (1.00) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL13591746 0.92 PTPN7 (1.00) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL588791 0.92 PTPN7 (1.00) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL3794459 0.92 HMGCR (1.00) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL3665801 0.92 HMGCR (1.00) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL411773 0.92 PTPN7 (1.00) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL414435 0.92 PTPN7 (1.00) HMGCRPTPN7TDP1ALDH1A1RECQL
SCHEMBL2350399 0.92 PTPN7 (1.00) HMGCRPTPN7TDP1ALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11504991-B2 Inkless printing on substrates and comestibles INTERCONTINENTAL GREAT BRANDS LLC (US) 2022-11-22 US disclosed
US-20200247167-A1 INKLESS PRINTING ON SUBSTRATES AND COMESTIBLES MONDELEZ UK R&D LIMITED (GB) 2020-08-06 US disclosed
US-20200232958-A1 PACKAGING MATERIAL COMPRISING INDICATOR RESPONDING TO AN EXTERNAL STIMULUS INTERCONTINENTAL GREAT BRANDS LLC 2020-07-23 US disclosed
EP-3669187-A2 INKLESS PRINTING ON SUBSTRATES AND COMESTIBLES Intercontinental Great Brands LLC (US) 2020-06-24 EP disclosed
EP-3669345-A1 INKLESS PRINTING ON SUBSTRATES AND COMESTIBLES Intercontinental Great Brands LLC (US) 2020-06-24 EP disclosed
WO-2019036342-A2 INKLESS PRINTING ON SUBSTRATES AND COMESTIBLES INTERCONTINENTAL GREAT BRANDS LLC (US) 2019-02-21 WO disclosed
EP-2678742-B1 REVERSIBLY ACTIVATABLE DIACETYLENES AND THEIR USE AS COLOUR-FORMERS DATALASE LTD (GB) 2018-08-29 EP disclosed
US-9581504-B2 Freeze, thaw and refreeze indicators based on rapid reactions in the solid state J P Laboratories (US) 2017-02-28 US disclosed
EP-2082890-B1 Thermoplastic material comprising polychromic substances DATALASE LTD (GB) 2015-08-19 EP disclosed
US-20140127429-A1 REVERSIBLY ACTIVATABLE DIACETYLENES AND THEIR USE AS COLOUR-FORMERS DATALASE LTD. (UK) 2014-05-08 US disclosed
US-20070071680-A1 Methods and compositions for preparing consumables with optical shifting properties SEGAN INDUSTRIES, INC. 2007-03-29 US disclosed
US-20050037498-A1 Plural intrinsic expiration initiation application indicators CMC Group, Inc. 2005-02-17 US disclosed
US-20040257918-A1 Plural intrinsic expiration initiation application indicators CMC Group, Inc. 2004-12-23 US disclosed
US-6787108-B2 Plural intrinsic expiration initiation application indicators CMC DAYMARK CORPORATION 2004-09-07 US disclosed
WO-2003085397-A2 PLURAL INTRINSIC EXPIRATION INITIATION APPLICATION INDICATORS CMC DAYMARK CORPORATION (US) 2003-10-16 WO disclosed
US-20030185706-A1 Plural intrinsic expiration initiation application indicators CMC Group, Inc. 2003-10-02 US disclosed
US-20030103905-A1 Methods and compositions for preparing consumables with optical shifting properties SEGAN INDUSTRIES 2003-06-05 US disclosed
EP-1297333-A2 INGESTIBLES POSSESSING INTRINSIC COLOR CHANGE Segan Industries, Inc. (US) 2003-04-02 EP disclosed
US-20020034475-A1 Ingestibles possessing intrinsic color change SEGAN INDUSTRIES 2002-03-21 US disclosed
WO-2002000920-A2 INGESTIBLES POSSESSING INTRINSIC COLOR CHANGE SEGAN INDUSTRIES, INC. (US) 2002-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030103905-A1 Methods and compositions for preparing consumables with optical shifting properties TAS2R46, THEM6, TAS2R41 HMGCR 4673/4885PTPN7 3762/4885TDP1 1698/4885
US-20020034475-A1 Ingestibles possessing intrinsic color change TAS2R46, THEM6, TAS2R16 HMGCR 4428/4885PTPN7 3807/4885TDP1 1792/4885
US-20070071680-A1 Methods and compositions for preparing consumables with optical shifting properties TAS2R46, THEM6, TAS2R41 HMGCR 4673/4885PTPN7 3762/4885TDP1 1698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.