SCHEMBL414809

SCHEMBL414809

O=C(CC(=O)OCC1CC2C=CC1C2)OCC1CC2C=CC1C2

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.41
KDM4E B2RXH2 9/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 5/20 0.37
TDP1 Q9NUW8 4/20 0.37
GAA P10253 1/20 0.36
POLB P06746 1/20 0.34
ALOX15 P16050 1/20 0.34
RAB9A P51151 1/20 0.34
PKM P14618 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8751808 0.90 EPHX2 (0.38) EPHX2KDM4ELMNAALDH1A1TDP1
SCHEMBL8614083 0.86 EPHX2 (0.40) EPHX2KDM4ELMNAALDH1A1TDP1
SCHEMBL1087442 0.86 EPHX2 (0.40) EPHX2KDM4ELMNAALDH1A1TDP1
SCHEMBL457240 0.86 KDM4E (0.41) EPHX2KDM4ELMNAALDH1A1TDP1
SCHEMBL4388376 0.86 KDM4E (0.38) EPHX2KDM4ELMNAALDH1A1TDP1
SCHEMBL14434848 0.85 KDM4E (0.39) EPHX2KDM4ELMNAALDH1A1TDP1
SCHEMBL4401217 0.85 KDM4E (0.39) EPHX2KDM4ELMNAALDH1A1TDP1
SCHEMBL18587123 0.84 KDM4E (0.41) EPHX2KDM4ELMNAALDH1A1TDP1
SCHEMBL455925 0.83 NLRP3 (0.43) EPHX2KDM4ELMNAALDH1A1TDP1
SCHEMBL6537290 0.83 KDM4E (0.39) EPHX2KDM4ELMNAALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795285-B2 Dual UV blockers containing stable photoactive mass polymerizable polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-10-24 US disclosed
US-20230295452-A1 HIGH IMPACT STRENGTH 3D PRINTING MATERIALS DERIVED FROM POLYCYCLOOLEFIN MONOMERS AND CROSSLINKERS PROMERUS, LLC (US) 2023-09-21 US disclosed
US-11697744-B2 High impact strength 3D printing materials derived from polycycloolefin monomers and crosslinkers PROMERUS, LLC (US) 2023-07-11 US disclosed
US-20230167256-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2023-06-01 US disclosed
US-20170357156-A1 NEGATIVE TONE PHOTOSENSITIVE COMPOSITIONS PROMERUS, LLC (US) 2017-12-14 US disclosed
US-8420293-B2 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2013-04-16 US disclosed
US-20120241250-A1 Aerial Work Platforms and Aerial Work Platform Assemblies Comprised of Polymerized Cycloolefin Monomers EAKIN GEORGE R (US) 2012-09-27 US disclosed
US-8200058-B2 Light guide and light guide structure SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-20120064458-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF PROMERUS, LLC (US) 2012-03-15 US disclosed
US-8053166-B2 Optical waveguides and methods thereof SUMITOMO BAKELITE CO. LTD. (JP) 2011-11-08 US disclosed
US-8021825-B2 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2011-09-20 US disclosed
US-7820356-B2 photo-induced thermally developable film comprising norbornene-type polyalkenamer copolymer and a procatalyst; curable; transparent or colorless, and propagation loss SUMITOMO BAKELITE CO. LTD. (JP) 2010-10-26 US disclosed
US-20100067861-A1 LIGHT GUIDE AND LIGHT GUIDE STRUCTURE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2010-03-18 US disclosed
US-20100061688-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062378-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20070148566-A1 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2007-06-28 US disclosed