SCHEMBL457240

SCHEMBL457240

CCC(=O)OCC1CC2C=CC1C2

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.41
ALDH1A1 P00352 4/20 0.41
EPHX2 P34913 3/20 0.36
POLB P06746 1/20 0.36
ALOX15 P16050 1/20 0.36
TDP1 Q9NUW8 3/20 0.35
LMNA P02545 1/20 0.35
PKM P14618 2/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL455925 0.87 NLRP3 (0.43) KDM4EALDH1A1EPHX2POLBALOX15
SCHEMBL414809 0.86 EPHX2 (0.41) KDM4EALDH1A1EPHX2POLBALOX15
SCHEMBL12798523 0.84 NLRP3 (0.40) KDM4EALDH1A1EPHX2
SCHEMBL8751808 0.84 EPHX2 (0.38) KDM4EALDH1A1EPHX2POLBALOX15
Acetic Acid SCHEMBL28542499 0.84 KDM4E (0.40) KDM4EALDH1A1EPHX2POLBALOX15
SCHEMBL6537290 0.84 KDM4E (0.39) KDM4EALDH1A1EPHX2POLBALOX15
SCHEMBL32688531 0.84 KDM4E (0.37) KDM4EALDH1A1EPHX2POLBALOX15
SCHEMBL1087442 0.83 EPHX2 (0.40) KDM4EALDH1A1EPHX2POLBALOX15
SCHEMBL8614083 0.83 EPHX2 (0.40) KDM4EALDH1A1EPHX2POLBALOX15
SCHEMBL13996248 0.83 NLRP3 (0.45) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2634197-B1 CATALYST FOR NORBORNENE MONOMER POLYMERIZATION AND METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO KK (JP) 2017-05-31 EP disclosed
EP-2614091-B1 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO KK (JP) 2016-04-20 EP disclosed
US-8835580-B2 Catalyst for norbornene monomer polymerization and method for producing norbornene polymer SHOWA DENKO K.K. (JP) 2014-09-16 US disclosed
US-8598288-B2 Catalyst for polymerization of norbornene monomers, method for producing norbornene polymer, method for producing norbornene copolymer, norbornene polymer and transition metal complex SHOWA DENKO K.K. (JP) 2013-12-03 US disclosed
US-20130261271-A1 CATALYST FOR NORBORNENE MONOMER POLYMERIZATION AND METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO K.K. (JP) 2013-10-03 US disclosed
EP-2634197-A1 CATALYST FOR NORBORNENE MONOMER POLYMERIZATION AND METHOD FOR PRODUCING NORBORNENE POLYMER Showa Denko K.K. (JP) 2013-09-04 EP disclosed
EP-2391661-B1 NORBORNENE COPOLYMER AND PRODUCTION METHOD THEREOF SHOWA DENKO KK (JP) 2013-07-31 EP disclosed
EP-2614091-A2 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER Showa Denko K.K. (JP) 2013-07-17 EP disclosed
EP-2599801-A1 CATALYST COMPOSITION, METHOD FOR PRODUCING NORBORNENE COPOLYMER USING CATALYST COMPOSITION, NORBORNENE COPOLYMER, AND HEAT RESISTANT FILM USING COPOLYMER Showa Denko K.K. (JP) 2013-06-05 EP disclosed
US-20130116113-A1 CATALYST COMPOSITION, PRODUCTION PROCESS FOR NORBORNENE BASE COPOLYMER BY USING CATALYST COMPOSITION, NORBORNENE BASE COPOLYMER AND HEAT RESISTANT FILM PREPARED BY USING THE SAME SHOWA DENKO K.K. (JP) 2013-05-09 US disclosed
US-20130059993-A1 CATALYST FOR POLYMERIZATION OF NORBORNENE MONOMERS, METHOD FOR PRODUCING NORBORNENE POLYMER, METHOD FOR PRODUCING NORBORNENE COPOLYMER, NORBORNENE POLYMER AND TRANSITION METAL COMPLEX SHOWA DENKO K.K. (JP) 2013-03-07 US disclosed
US-8163860-B2 Norbornene copolymer and production method thereof SHOWA DENKO K.K. (JP) 2012-04-24 US disclosed
WO-2012033227-A2 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO K.K. (JP) 2012-03-15 WO disclosed
US-20110282014-A1 NORBORNENE COPOLYMER AND PRODUCTION METHOD THEREOF RIKEN (JP) 2011-11-17 US disclosed
WO-2010087528-A2 NORBORNENE COPOLYMER AND PRODUCTION METHOD THEREOF SHOWA DENKO K.K. (JP) 2010-08-05 WO disclosed
US-7714087-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2010-05-11 US disclosed
US-20090137757-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof IMUTA JUNICHI 2009-05-28 US disclosed
US-20080199805-A1 PHOTOSENSITIVE COMPOSITIONS EMPLOYING SILICON-CONTAINING ADDITIVES FUJIFILM ELECTRONIC MATERIALS. U.S.A., INC. 2008-08-21 US disclosed
WO-2008098189-A1 PHOTOSENSITIVE COMPOSITIONS EMPLOYING SILICON-CONTAINING ADDITIVES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2008-08-14 WO disclosed
US-7393907-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2008-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059993-A1 CATALYST FOR POLYMERIZATION OF NORBORNENE MONOMERS, METHOD FOR PRODUCING NORBORNENE POLYMER, METHOD FOR PRODUCING NORBORNENE COPOLYMER, NORBORNENE POLYMER AND TRANSITION METAL COMPLEX NNMT, PPOX, DNMT1 KDM4E 3501/4885ALDH1A1 277/4885EPHX2 3348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.