SCHEMBL4148161

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4134613	0.89	IL6 (0.84)	IL6MEN1KMT2AGRIN1GRIN2B
	SCHEMBL4582037	0.89	IL6 (0.72)	IL6MAPK14MEN1KMT2AGRIN1
	SCHEMBL4127299	0.89	IL6 (0.82)	IL6MEN1KMT2AHTR2CMAPT
	SCHEMBL4579012	0.88	IL6 (0.73)	IL6MAPK14MEN1KMT2AHTR2C
	SCHEMBL4579844	0.88	IL6 (0.90)	IL6MEN1KMT2AHTR2CFFAR1
	SCHEMBL4582012	0.86	IL6 (0.79)	IL6GRIN1GRIN2BHTR2CMAPT
	SCHEMBL4581924	0.86	IL6 (0.75)	IL6MAPK14MEN1KMT2AGRIN1
	SCHEMBL1917741	0.85	IL6 (0.89)	IL6GRIN1GRIN2BHTR2CCHEK1
	SCHEMBL4580952	0.85	IL6 (0.86)	IL6MEN1KMT2AHTR2CFFAR1
	SCHEMBL4581163	0.85	IL6 (0.82)	IL6MEN1KMT2AGRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.