SCHEMBL4148198

SCHEMBL4148198

CCOC(=O)C(C(C)=O)C(C)CC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.42
LMNA P02545 2/20 0.42
HSD17B10 Q99714 1/20 0.42
TP53 P04637 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
GAA P10253 2/20 0.36
ALOX15 P16050 2/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
TRPA1 O75762 1/20 0.33
GLO1 Q04760 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4191467 0.89 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10TP53SMN1; SMN2
Ethane SCHEMBL27513819 0.86 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TP53SMN1; SMN2
SCHEMBL4944171 0.84 ALDH1A1 (0.52) ALDH1A1LMNAHSD17B10TP53SMN1; SMN2
SCHEMBL10869191 0.83 TP53 (0.43) ALDH1A1LMNAHSD17B10TP53SMN1; SMN2
SCHEMBL11105470 0.83 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10HPGDNPSR1
SCHEMBL3799883 0.83 SMN1; SMN2 (0.46) ALDH1A1SMN1; SMN2MAPTKMT2ACA1
SCHEMBL1919905 0.82 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10TP53SMN1; SMN2
SCHEMBL10253096 0.82 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10TP53SMN1; SMN2
SCHEMBL17085270 0.82 ALDH1A1 (0.41) ALDH1A1HSD17B10TP53SMN1; SMN2KMT2A
SCHEMBL23825329 0.81 ALDH1A1 (0.35) ALDH1A1ALOX15L3MBTL1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3625278-A1 POLYURETHANE COATING COMPOSITION SWIMC LLC (US) 2020-03-25 EP claimed
CN-110691800-A Polyurethane coating composition 宣伟投资管理有限公司 2020-01-14 CN claimed
WO-2018213694-A1 POLYURETHANE COATING COMPOSITION SWIMC LLC (US) 2018-11-22 WO claimed
EP-4077455-B1 NON AQUEOUS CROSSLINKABLE COMPOSITION ALLNEX NETHERLANDS BV (NL) 2024-06-12 EP disclosed
CN-114846049-B Nonaqueous crosslinkable compositions 湛新荷兰有限公司 2024-05-24 CN disclosed
EP-4359482-A1 NON AQUEOUS CROSSLINKABLE COMPOSITION Allnex Netherlands B.V. (NL) 2024-05-01 EP disclosed
US-20230392028-A1 POLYURETHANE COATING COMPOSITION SWIMC LLC (US) 2023-12-07 US disclosed
CN-113544181-B Non-aqueous crosslinkable compositions 湛新荷兰有限公司 2023-08-08 CN disclosed
US-20230026705-A1 NON AQUEOUS CROSSLINKABLE COMPOSITION ALLNEX NETHERLANDS B.V. (NL) 2023-01-26 US disclosed
WO-2022268669-A1 NON AQUEOUS CROSSLINKABLE COMPOSITION ALLNEX NETHERLANDS B.V. (NL) 2022-12-29 WO disclosed
WO-2021122978-A1 NON AQUEOUS CROSSLINKABLE COMPOSITION ALLNEX NETHERLANDS B.V. (NL) 2021-06-24 WO disclosed
US-20200079965-A1 POLYURETHANE COATING COMPOSITION SWIMC LLC (US) 2020-03-12 US disclosed
US-20090137557-A1 Calcilytic Compounds SMITHKLINE BEECHAM CORPORATION 2009-05-28 US disclosed
US-20090042917-A1 Aminopyrimidine Derivative and Plant Disease Control Agent for Agricultural or Horticultural Use KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2009-02-12 US disclosed
EP-2006288-A1 AMINOPYRIDINE DERIVATIVE AND PLANT DISEASE CONTROL AGENT FOR AGRICULTURAL OR HORTICULTURAL USE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2008-12-24 EP disclosed
EP-1951244-A2 CALCILYTIC COMPOUNDS SmithKline Beecham Corporation (US) 2008-08-06 EP disclosed
WO-2007062370-A2 CALCILYTIC COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2007-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090042917-A1 Aminopyrimidine Derivative and Plant Disease Control Agent for Agricultural or Horticultural Use DPYD, PM20D2, PDCD11 ALDH1A1 1884/4885LMNA 4597/4885HSD17B10 1821/4885
US-20090137557-A1 Calcilytic Compounds CALCR, SOST, CALCB ALDH1A1 4674/4885LMNA 1316/4885HSD17B10 3264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.