SCHEMBL4148435

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4131851	0.95	IL6 (0.73)	IL6AKR1B1MEN1KMT2AALDH1A1
	SCHEMBL4581224	0.90	IL6 (0.72)	IL6MEN1KMT2AALDH1A1LMNA
	SCHEMBL4148280	0.90	IL6 (0.74)	IL6MEN1KMT2AALDH1A1LMNA
	SCHEMBL4140752	0.89	IL6 (0.70)	IL6MEN1KMT2AALDH1A1LMNA
	SCHEMBL4582167	0.89	IL6 (0.70)	IL6MEN1KMT2AALDH1A1LMNA
	SCHEMBL4581342	0.89	IL6 (0.84)	IL6AKR1B1MEN1KMT2AALDH1A1
	SCHEMBL4582222	0.89	IL6 (0.72)	IL6MEN1KMT2AALDH1A1TP53
	SCHEMBL4135574	0.88	IL6 (0.69)	IL6MEN1KMT2AALDH1A1LMNA
	SCHEMBL4581352	0.88	IL6 (0.71)	IL6MEN1KMT2AALDH1A1LMNA
	SCHEMBL4580863	0.88	IL6 (0.71)	IL6MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.