SCHEMBL414928

SCHEMBL414928

c1ccc2c3c(ccc2c1)Oc1ccc2ccccc2c1C3

nearest known ligand 0.72

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.59
KDM4E B2RXH2 2/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C19 P33261 2/20 0.59
SIRT1 Q96EB6 2/20 0.59
GLA P06280 1/20 0.59
CYP2C9 P11712 1/20 0.59
HPGD P15428 1/20 0.59
MAPT P10636 1/20 0.47
ALDH1A1 P00352 2/20 0.46
CYP2A6 P11509 1/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
SIRT2 Q8IXJ6 3/20 0.43
HPRT1 P00492 1/20 0.42
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
GPR84 Q9NQS5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29688038 1.00 HSD17B10 (0.59) HSD17B10KDM4ECYP1A2CYP2C19SIRT1
SCHEMBL79264 0.87 MAOA (0.55) HSD17B10KDM4ECYP1A2CYP2C19SIRT1
SCHEMBL30688778 0.87 MAOA (0.55) HSD17B10KDM4ECYP1A2CYP2C19SIRT1
SCHEMBL29370052 0.87 MAOA (0.55) HSD17B10KDM4ECYP1A2CYP2C19SIRT1
SCHEMBL14677465 0.84 SIRT1 (0.72) HSD17B10KDM4ECYP1A2CYP2C19SIRT1
SCHEMBL10378227 0.81 KDM4E (0.54) HSD17B10KDM4ECYP1A2CYP2C19SIRT1
SCHEMBL11434161 0.81 KDM4E (0.43) HSD17B10KDM4ECYP1A2CYP2C19SIRT1
SCHEMBL12949861 0.79 KDM4E (0.44) HSD17B10KDM4ECYP1A2CYP2C19SIRT1
SCHEMBL668167 0.79 MAOA (0.50) HSD17B10KDM4ECYP1A2CYP2C19SIRT1
SCHEMBL31329296 0.79 MAOA (0.50) HSD17B10KDM4ECYP1A2CYP2C19SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767398-B2 Spin-on compositions comprising an inorganic oxide component and an alkynyloxy substituted spin-on carbon component useful as hard masks and filling materials with improved shelf life MERCK PATENT GMBH (DE) 2023-09-26 US disclosed
US-11767398-B2 Spin-on compositions comprising an inorganic oxide component and an alkynyloxy substituted spin-on carbon component useful as hard masks and filling materials with improved shelf life MERCK PATENT GMBH (DE) 2023-09-26 US disclosed
US-20220025109-A1 SPIN-ON COMPOSITIONS COMPRISING AN INORGANIC OXIDE COMPONENT AND AN ALKYNYLOXY SUBSTITUTED SPIN-ON CARBON COMPONENT USEFUL AS HARD MASKS AND FILLING MATERIALS WITH IMPROVED SHELF LIFE MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2022-01-27 US disclosed
US-11137686-B2 Material for forming underlayer film for lithography, composition for forming underlayer film for lithography, underlayer film for lithography and production method thereof, and resist pattern forming method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-10-05 US disclosed
CN-105859619-B The method of the ionic liquid-catalyzed multi-component reaction synthesis acridine cyclohexadione compounds of betaines 河南师范大学 2019-01-01 CN disclosed
EP-3350190-A1 BRØNSTED-ACID FLUOROALKYL PHOSPHONATES Merck Patent GmbH (DE) 2018-07-25 EP disclosed
US-20180074402-A1 RESIST COMPOSITION, METHOD FOR FORMING RESIST PATTERN, AND POLYPHENOL COMPOUND USED THEREIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-03-15 US disclosed
US-20170240690-A1 EPOXY RESIN, CURABLE RESIN COMPOSITION, CURED PRODUCT, SEMICONDUCTOR ENCAPSULATING MATERIAL, SEMICONDUCTOR DEVICE, PREPREG, CIRCUIT BOARD, BUILDUP FILM, BUILDUP SUBSTRATE, FIBER-REINFORCED COMPOSITE MATERIAL AND FIBER-REINFORCED MOLDED ARTICLE DIC CORPORATION (JP) 2017-08-24 US disclosed
US-20170240690-A1 EPOXY RESIN, CURABLE RESIN COMPOSITION, CURED PRODUCT, SEMICONDUCTOR ENCAPSULATING MATERIAL, SEMICONDUCTOR DEVICE, PREPREG, CIRCUIT BOARD, BUILDUP FILM, BUILDUP SUBSTRATE, FIBER-REINFORCED COMPOSITE MATERIAL AND FIBER-REINFORCED MOLDED ARTICLE DIC CORPORATION (JP) 2017-08-24 US disclosed
WO-2017045745-A1 BRØNSTED-ACID FLUOROALKYL PHOSPHONATES MERCK PATENT GMBH (DE) 2017-03-23 WO disclosed
EP-1043338-A1 Polymerisation process in a reactor with double coating against scale formation SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-10-11 EP disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-6037426-A POLYMERIZING MONOMER HAVING ETHYLENIC DOUBLE BOND IN POLYMERIZATION VESSEL HAVING BILAYER POLYMER SCALE PREVENTIVE COATING FILM ON INNER WALL SURFACES SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-03-14 US disclosed
EP-0934955-A1 Polymerization process characterized by a two layer coating against scale formation deposited using a steam carrier SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-08-11 EP disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180074402-A1 RESIST COMPOSITION, METHOD FOR FORMING RESIST PATTERN, AND POLYPHENOL COMPOUND USED THEREIN SLC11A2, ABCC1, FBL HSD17B10 1280/4885KDM4E 2209/4885CYP1A2 955/4885
US-11137686-B2 Material for forming underlayer film for lithography, composition for forming underlayer film for lithography, underlayer film for lithography and production method thereof, and resist pattern forming method MLLT1, PRDM9, NAP1L1 HSD17B10 2039/4885KDM4E 203/4885CYP1A2 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.