SCHEMBL668167

SCHEMBL668167

c1ccc2c(c1)Cc1c(ccc3c1ccc1ccccc13)O2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
HPRT1 P00492 3/20 0.45
CYP1A2 P05177 3/20 0.44
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 2/20 0.44
CYP2C19 P33261 2/20 0.44
GLA P06280 1/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 1/20 0.44
SIRT1 Q96EB6 1/20 0.44
ALDH1A1 P00352 2/20 0.39
CYP2A6 P11509 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPKAPK2 P49137 1/20 0.38
MAPT P10636 2/20 0.36
HNF4A P41235 1/20 0.36
PAX8 Q06710 1/20 0.35
LCK P06239 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31329296 1.00 MAOA (0.50) MAOAMAOBHPRT1CYP1A2HSD17B10
SCHEMBL30688778 0.92 MAOA (0.55) MAOAMAOBCYP1A2HSD17B10KDM4E
SCHEMBL79264 0.92 MAOA (0.55) MAOAMAOBCYP1A2HSD17B10KDM4E
SCHEMBL29370052 0.92 MAOA (0.55) MAOAMAOBCYP1A2HSD17B10KDM4E
Water SCHEMBL27261398 0.90 MAOA (0.53) MAOAMAOBCYP1A2HSD17B10KDM4E
SCHEMBL29876714 0.83 MAOA (0.42) MAOAMAOBCYP1A2HSD17B10KDM4E
Hypophosphorous Acid SCHEMBL29912580 0.80 MAOA (0.39) MAOAMAOBCYP1A2HSD17B10KDM4E
SCHEMBL414928 0.79 HSD17B10 (0.59) HPRT1CYP1A2HSD17B10KDM4ECYP2C19
SCHEMBL29688038 0.79 HSD17B10 (0.59) HPRT1CYP1A2HSD17B10KDM4ECYP2C19
SCHEMBL3674511 0.77 MAOA (0.46) MAOAMAOBCYP1A2HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1521 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4083174-B1 REFRIGERATION CYCLE DEVICE, REFRIGERATION MACHINE OIL AND REFRIGERANT LEAKAGE PREVENTION AGENT DAIKIN IND LTD (JP) 2025-01-22 EP claimed
CN-117343037-B Spirofluorene naphthoxanthene organic blue light material and preparation method and application thereof 山东浩华新材料科技有限公司 2024-12-03 CN claimed
WO-2024199766-A1 ABSORPTION INCREASE, EFFICIENCY ENHANCEMENT AND SPATIAL LIGHT MODULATION BY MICRO-STRUCTURING COLOR CONVERSION LAYERS SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2024-10-03 WO claimed
EP-3299435-B1 METHOD OF PREPARING A COMPOSITION COMPRISING HFC-1234YF CHEMOURS CO FC LLC (US) 2024-06-26 EP claimed
EP-3309233-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-152A CHEMOURS CO FC LLC (US) 2024-02-21 EP claimed
CN-117343037-A Spirofluorene naphthoxanthene organic blue light material and preparation method and application thereof 山东浩华新材料科技有限公司 2024-01-05 CN claimed
EP-4074807-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN The Chemours Company FC, LLC (US) 2022-10-19 EP claimed
EP-1985680-B2 Composition comprising a HFC-1234ze isomer CHEMOURS CO FC LLC (US) 2022-06-29 EP claimed
US-20210355360-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF THE CHEMOURS COMPANY FC, LLC (US) 2021-11-18 US claimed
US-20210207014-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF THE CHEMOURS COMPANY FC, LLC (US) 2021-07-08 US claimed
US-20050156139-A1 1-Ethoxy-1,1,2,2,3,3,4,4,4,-nonafluorobutane refrigerant compositions comprising a fluoroether and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-21 US claimed
US-20050156134-A1 1,1,1,2,2,3,3,4,4,-Nonafluoro-4-methoxybutane refrigerant compositions comprising a fluoroether and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-21 US claimed
US-20050156135-A1 Refrigerant compositions comprising 1-ethoxy-1,1,2,2,3,4,4,4-nonafluorobutane and a hydrofluorocarbon and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-21 US claimed
US-20050151113-A1 Hydrofluorocarbon refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US claimed
US-20050151110-A1 Fluoroether refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US claimed
US-20050151111-A1 1,1,1,3,3-Pentafluorobutane refrigerant or heat transfer fluid compositions comprising hydrofluorocarbon and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US claimed
US-20050151112-A1 1,1,1,2,2,3,3,4,4-Nonafluoro-4-methoxybutane refrigerant compositions comprising hydrofluorocarbon, and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US claimed
US-20050145822-A1 Refrigerant compositions comprising UV fluorescent dye and solubilizing agent E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-07 US claimed
WO-2005049761-A1 REFRIGERANT COMPOSITIONS COMPRISING UV FLUORESCENT DYE AND SOLUBILIZING AGENT E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-06-02 WO claimed
US-4758366-A Polyhalogenated hydrocarbon refrigerants and refrigerant oils colored with fluorescent dyes and method for their use as leak detectors WIDGER CHEMICAL CORPORATION (US) 1988-07-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210355360-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF GFPT1, PFAS, TRMT1 MAOA 2077/4885MAOB 2025/4885HPRT1 231/4885
US-20210207014-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF GFPT1, PFAS, TRMT1 MAOA 2077/4885MAOB 2025/4885HPRT1 231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.