Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PLEC | Q15149 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11987697 | 0.87 | EDNRA (0.38) | APPKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6139408 | 0.75 | MEN1 (0.42) | KMT2AMEN1KDM4EALDH1A1EDNRA | |
| SCHEMBL14567783 | 0.74 | EDNRA (0.36) | KMT2AMEN1KDM4EALDH1A1EDNRA | |
| SCHEMBL5101405 | 0.71 | EPHX1 (0.44) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL14277075 | 0.69 | EDNRA (0.38) | KMT2AMEN1KDM4EALDH1A1EDNRA | |
| SCHEMBL11987704 | 0.67 | KDM4E (0.39) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3199683 | 0.67 | MTNR1A (0.42) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL12777506 | 0.67 | KMT2A (0.52) | CA1CA2MAPTKMT2AMEN1 | |
| SCHEMBL14277057 | 0.66 | CASP6 (0.37) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL14567777 | 0.65 | KMT2A (0.33) | KMT2AMEN1KDM4EALDH1A1EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247158-B2 | Molecular resists based on functionalized polycarbocycles | ARGITIS PANAGIOTIS (GR) | 2012-08-21 | — | — | US | disclosed |
| US-20090220887-A1 | Molecular Resists Based On Functionalized Polycarbocycles | NATIONAL CENTER FOR SCIENTIFIC RESEARCH | 2009-09-03 | — | — | US | disclosed |
| EP-1941324-A2 | MOLECULAR RESISTS BASED ON FUNCTIONALIZED POLYCARBOCYCLES | National Center for Scientific Research Demokritos (GR) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007031803-A2 | MOLECULAR RESISTS BASED ON FUNCTIONALIZED POLYCARBOCYCLES | NATIONAL CENTER FOR SCIENTIFIC RESEARCH (NCSR) ''DEMOKRITOS'' (GR) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090220887-A1 | Molecular Resists Based On Functionalized Polycarbocycles | POLL, CLTB, PCNA | CA1 4497/4885CA2 3552/4885APP 2188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.