SCHEMBL3199683

SCHEMBL3199683

CC(C)(C)OC(=O)Cc1c2ccccc2cc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 2/20 0.42
MTNR1B P49286 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HTR2A P28223 1/20 0.42
ALDH1A1 P00352 4/20 0.41
HPGD P15428 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 2/20 0.41
GLA P06280 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
GPR35 Q9HC97 2/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.39
KDM4A O75164 1/20 0.39
GAA P10253 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12690103 0.82 EPHX1 (0.40) L3MBTL1HTR2AALDH1A1HPGDMEN1
SCHEMBL12325616 0.82 KMT2A (0.42) L3MBTL1HTR2AALDH1A1HPGDMEN1
SCHEMBL27887680 0.82 ALDH1A1 (0.41) MTNR1AMTNR1BL3MBTL1ALDH1A1HPGD
SCHEMBL3199606 0.81 EGFR (0.51) L3MBTL1HTR2AALDH1A1HPGDMEN1
SCHEMBL25067042 0.80 NCEH1 (0.37) MTNR1AMTNR1BKDM4A
SCHEMBL3197961 0.79 MTNR1A (0.41) MTNR1AMTNR1BL3MBTL1ALDH1A1HPGD
SCHEMBL28195038 0.79 HTR2A (0.50) L3MBTL1HTR2AALDH1A1HPGDMEN1
SCHEMBL28087180 0.78 HTR2A (0.50) L3MBTL1HTR2AALDH1A1HPGDMEN1
SCHEMBL11987697 0.78 EDNRA (0.38) L3MBTL1HTR2AALDH1A1HPGDMEN1
SCHEMBL2914936 0.77 SIRT5 (0.59) L3MBTL1ALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1840650-B1 Positive type radiation-sensitive resin composition JSR CORP (JP) 2009-03-18 EP claimed
EP-1840650-A1 Positive type radiation-sensitive resin composition JSR Corporation (JP) 2007-10-03 EP claimed
US-20060223010-A1 Positive type radiation-sensitive resin composition JSR CORPORATION (JP) 2006-10-05 US claimed
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1840650-B1 Positive type radiation-sensitive resin composition JSR CORP (JP) 2009-03-18 EP disclosed
US-7488566-B2 Positive type radiation-sensitive resin composition JSR CORPORATION (JP) 2009-02-10 US disclosed
EP-1640804-B1 Positive-tone radiation-sensitive resin composition JSR CORP (JP) 2008-11-19 EP disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7335457-B2 Positive-tone radiation-sensitive resin composition JSR CORPORATION (JP) 2008-02-26 US disclosed
EP-1840650-A1 Positive type radiation-sensitive resin composition JSR Corporation (JP) 2007-10-03 EP disclosed
US-20060223010-A1 Positive type radiation-sensitive resin composition JSR CORPORATION (JP) 2006-10-05 US disclosed
US-20060078821-A1 A caroboxyalkylanthracene based compound, a hydroxy or alkoxystyrene polymer, and a sulfonimide compound as photoacid generator; low sublimation properties and excellent compatibility with other components; exhibits optimum controllability of radiation transmittance; microfabrication JSR CORPORATION (JP) 2006-04-13 US disclosed
EP-1640804-A2 Positive-tone radiation-sensitive resin composition JSR Corporation (JP) 2006-03-29 EP disclosed