Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13906899 | 0.90 | MAPK14 (0.33) | MAPK14 | |
| SCHEMBL1887290 | 0.84 | MAPK14 (0.39) | MAPK14KDM4EMEN1NPC1MAPT | |
| SCHEMBL4863732 | 0.82 | GPR6 (0.34) | MAPK14PIM1PIM2 | |
| SCHEMBL4160305 | 0.82 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL4162294 | 0.80 | — | — | |
| SCHEMBL4164674 | 0.78 | MAPK14 (0.32) | MAPK14 | |
| SCHEMBL4155726 | 0.78 | MAPK14 (0.31) | MAPK14 | |
| SCHEMBL4718007 | 0.77 | CSNK2A1 (0.32) | — | |
| SCHEMBL1882014 | 0.77 | LATS1 (0.41) | — | |
| SCHEMBL5224972 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069333-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-03-12 | — | — | US | disclosed |
| US-20090069333-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-03-12 | — | — | US | disclosed |
| US-20090069333-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-03-12 | — | — | US | disclosed |
| US-7410967-B2 | Pyridodiazines as plant fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-7410967-B2 | Pyridodiazines as plant fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-7410967-B2 | Pyridodiazines as plant fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| EP-1575948-B1 | PYRIDODIAZINES AS PLANT FUNGICIDES | SYNGENTA LTD (GB) | 2007-02-14 | — | — | EP | disclosed |
| EP-1575948-B1 | PYRIDODIAZINES AS PLANT FUNGICIDES | SYNGENTA LTD (GB) | 2007-02-14 | — | — | EP | disclosed |
| US-20060205717-A1 | Pyridodiazines as plant fungicides | SYNGENTA CROP PROTECTION, INC. | 2006-09-14 | — | — | US | disclosed |
| EP-1575948-A1 | PYRIDODIAZINES AS PLANT FUNGICIDES | Syngenta Limited (GB) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056825-A1 | PYRIDODIAZINES AS PLANT FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069333-A1 | FUNGICIDES | CYP4Z1, CYP4X1, PRXL2A | MAPK14 2124/4885PIM1 812/4885PIM2 708/4885 |
| US-20060205717-A1 | Pyridodiazines as plant fungicides | CYP4Z1, CYP4X1, PNPO | MAPK14 2007/4885PIM1 2488/4885PIM2 2634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.