Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289330 | 0.80 | FADS1 (0.50) | GAANPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL482522 | 0.80 | HPGD (0.57) | NPC1SMN1; SMN2RAB9AHTTMAPT | |
| SCHEMBL6805383 | 0.78 | MMP3 (0.56) | MEN1KMT2AGAANPC1SMN1; SMN2 | |
| SCHEMBL7641652 | 0.77 | MEN1 (0.59) | MEN1KMT2ATDP1NPC1SMN1; SMN2 | |
| SCHEMBL5123859 | 0.76 | HTT (0.55) | MEN1KMT2ATDP1LMNAGAA | |
| SCHEMBL6110708 | 0.76 | JAK2 (0.52) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL10532020 | 0.76 | DDX3X (0.44) | KMT2ALMNAGAAMAPTALDH1A1 | |
| SCHEMBL429187 | 0.75 | PTPN1 (0.48) | MEN1KMT2ATDP1NPC1SMN1; SMN2 | |
| SCHEMBL9725165 | 0.74 | SMN1; SMN2 (0.44) | MEN1KMT2ALMNANPC1SMN1; SMN2 | |
| SCHEMBL27888664 | 0.73 | MEN1 (0.57) | MEN1KMT2ALMNANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009078587-A2 | COMPOSITION FOR PREVENTION AND TREATMENT OF CANCER CONTAINING TRIAZOLYL-THIO-ETHANONE DERIVATIVES INHIBITING ACTIVITY OF PROTEIN PHOSPHATASES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS AN ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-06-25 | — | — | WO | disclosed |