Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1040588 | 0.78 | NOS2 (0.50) | NOS2CES2CES1AKR1B1GRIN1 | |
| SCHEMBL2500288 | 0.73 | CES2 (0.48) | NOS2CES2CES1AKR1B1GRIN1 | |
| SCHEMBL3686805 | 0.72 | NOS2 (0.44) | NOS2CES2CES1AKR1B1GRIN1 | |
| SCHEMBL817467 | 0.71 | NOS2 (0.42) | NOS2CES2CES1AKR1B1GRIN1 | |
| SCHEMBL11810722 | 0.71 | CES1 (0.52) | GPR52CES2CES1AKR1B1ALDH1A1 | |
| SCHEMBL4155184 | 0.71 | GLA (0.36) | CES2CES1ALDH1A1LMNACYP2D6 | |
| SCHEMBL7451798 | 0.71 | GLA (0.36) | CES2CES1ALDH1A1LMNACYP2D6 | |
| SCHEMBL1245524 | 0.71 | CES1 (0.52) | GPR52CES2CES1AKR1B1ALDH1A1 | |
| SCHEMBL11810715 | 0.71 | CES1 (0.52) | GPR52CES2CES1AKR1B1ALDH1A1 | |
| SCHEMBL817534 | 0.71 | NOS2 (0.42) | NOS2CES2CES1AKR1B1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | LABORATORIOS SALVAT, S.A. (ES) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | PPARG, PPARD, TYRO3 | NOS2 1059/4885GPR52 501/4885CES2 1150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.