Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2500288 | 0.81 | CES2 (0.48) | NOS2ALDH1A1CES2CES1AKR1B1 | |
| SCHEMBL3686805 | 0.80 | NOS2 (0.44) | NOS2ALDH1A1LMNACES2CES1 | |
| SCHEMBL6246264 | 0.78 | MEN1 (0.44) | ALDH1A1LMNACTBP2KDM4ESMN1; SMN2 | |
| SCHEMBL818281 | 0.78 | L3MBTL1 (0.42) | NOS2ALDH1A1LMNACES2CES1 | |
| SCHEMBL8393618 | 0.78 | ALDH1A1 (0.61) | ALDH1A1LMNAKEAP1GRIN2BGRIN1 | |
| SCHEMBL816881 | 0.78 | NOS2 (0.42) | NOS2ALDH1A1LMNACES2CES1 | |
| SCHEMBL817534 | 0.78 | NOS2 (0.42) | NOS2ALDH1A1LMNACES2CES1 | |
| SCHEMBL817467 | 0.78 | NOS2 (0.42) | NOS2ALDH1A1LMNACES2CES1 | |
| SCHEMBL4150306 | 0.78 | NOS2 (0.39) | NOS2ALDH1A1LMNACES2CES1 | |
| SCHEMBL689470 | 0.77 | GRIN2B (0.50) | NOS2CES2CES1AKR1B1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198426-B2 | Use of 5 pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | claimed |
| EP-2378880-A1 | USE OF 5-PYRIDIN-4YL(1,3)THIAZOLE FOR TREATING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AG (DE) | 2011-10-26 | — | — | EP | claimed |
| US-20100168185-A1 | Use of 5-pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | BAYER CORPSCIENCE AG (DE) | 2010-07-01 | — | — | US | claimed |
| WO-2010069494-A1 | USE OF 5-PYRIDIN-4YL(1,3)THIAZOLE FOR TREATING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-06-24 | — | — | WO | claimed |
| EP-2198710-A1 | Use of 5-pyridin-4yl-(1,3) thiazoles for combating phytopathogenic fungi | Bayer CropScience AG (DE) | 2010-06-23 | — | — | EP | claimed |
| US-20080262070-A1 | Pharmaceutically Active Tetrahydro-Pyrrolizinone Compounds | BAUMANN KARL | 2008-10-23 | — | — | US | claimed |
| WO-2001041763-A1 | TREATMENT OF ADDICTION DISORDERS | UNIVERSITY OF CINCINNATI (US) | 2001-06-14 | — | — | WO | claimed |
| US-6143932-A | FOR EFFECTING ANALGESIA, A DECREASE IN THE POSTPRANDIAL RISE IN THE BLOOD GLUCOSE LEVELS OF A MAMMAL AFTER INGESTION OF A CARBOHYDRATE LOAD BY SAID MAMMAL, AND TREATING MICROBIAL INFECTIONS | TREGA BIOSCIENCES, INC. (US) | 2000-11-07 | — | — | US | claimed |
| US-6121489-A | Selectively N-alkylated peptidomimetic combinatorial libraries and compounds therein | TREGA BIOSCIENCES, INC. (US) | 2000-09-19 | — | — | US | claimed |
| EP-0890101-A4 | SELECTIVELY N-ALKYLATED PEPTIDOMIMETIC COMBINATORIAL LIBRARIES AND COMPOUNDS THEREIN | TORREY PINES INST (US) | 1999-12-08 | — | — | EP | claimed |
| EP-0890101-A1 | SELECTIVELY N-ALKYLATED PEPTIDOMIMETIC COMBINATORIAL LIBRARIES AND COMPOUNDS THEREIN | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1999-01-13 | — | — | EP | claimed |
| WO-1997033174-A1 | SELECTIVELY N-ALKYLATED PEPTIDOMIMETIC COMBINATORIAL LIBRARIES AND COMPOUNDS THEREIN | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-09-12 | — | — | WO | claimed |
| WO-2024107323-A1 | HETEROGENEOUS CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-05-23 | — | — | WO | disclosed |
| EP-3538263-B1 | METHODS TO REJUVENATE A DEACTIVATED HYDROFORMYLATION CATALYST SOLUTION | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-3538264-B1 | METHODS TO REJUVENATE A DEACTIVATED HYDROFORMYLATION CATALYST SOLUTION | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-3538265-B1 | METHODS OF TREATING A HYDROFORMYLATION CATALYST SOLUTION | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2023-09-27 | — | — | EP | disclosed |
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |
| EP-0081119-A1 | Room temperature vulcanizable polyorganosiloxane compositions containing alcoholic and carboxylic organofunctionality | Toray Silicone Company Limited (JP) | 1983-06-15 | — | — | EP | disclosed |
| EP-0002836-B1 | ACYLHYDROCARBYLAMINOALCANECARBOXYLIC ACIDS, THEIR PREPARATION AND THEIR USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-10-27 | — | — | EP | disclosed |
| US-4268688-A | OF OLEFINS | MONSANTO COMPANY (US) | 1981-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168185-A1 | Use of 5-pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | PIR, PNPO, PDXK | NOS2 2704/4885ALDH1A1 2137/4885LMNA 1421/4885 |
| US-20080262070-A1 | Pharmaceutically Active Tetrahydro-Pyrrolizinone Compounds | VCAM1, ICAM1, EPCAM | NOS2 2096/4885ALDH1A1 164/4885LMNA 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.