Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1904632 | 0.86 | DHODH (0.73) | DHODHNPSR1CYP3A4CYP2D6MAPT | |
| SCHEMBL25069374 | 0.85 | DHODH (0.63) | DHODHNPSR1CYP3A4CYP2D6MAPT | |
| SCHEMBL10474559 | 0.84 | DHODH (0.52) | DHODHNPSR1CYP3A4CYP2D6MAPT | |
| SCHEMBL10474560 | 0.84 | DHODH (0.52) | DHODHNPSR1CYP3A4CYP2D6MAPT | |
| SCHEMBL1429754 | 0.83 | DHODH (0.70) | DHODHNPSR1CYP3A4CYP2D6MAPT | |
| SCHEMBL1429843 | 0.83 | DHODH (0.70) | DHODHNPSR1CYP3A4CYP2D6MAPT | |
| SCHEMBL10862609 | 0.83 | MAPT (0.76) | DHODHNPSR1CYP3A4CYP2D6MAPT | |
| SCHEMBL10988529 | 0.83 | DHODH (0.70) | DHODHNPSR1CYP3A4CYP2D6MAPT | |
| SCHEMBL4742564 | 0.83 | NPSR1 (0.72) | DHODHNPSR1CYP3A4CYP2D6MAPT | |
| SCHEMBL846104 | 0.82 | DHODH (0.77) | DHODHNPSR1CYP3A4CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186918-A1 | Triazole Compounds as Lipoxygenase Inhibitors | BIOLIPOX AB (SE) | 2009-07-23 | — | — | US | disclosed |
| CN-100457737-C | Quinolyl amide derivative and its prepn process and use | INST PHARM & TOXICOLOGY AMMS (CN) | 2009-02-04 | — | — | CN | disclosed |
| WO-2008093940-A1 | QUINOLINE DERIVATIVES AS CASPASE-3 INHIBITOR, PREPARATION PROCESS FOR THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |
| CN-1847226-A | Quinolyl amide derivative and its prepn process and use | INST OF TOXICANT PHARMACOLOGY (CN) | 2006-10-18 | — | — | CN | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186918-A1 | Triazole Compounds as Lipoxygenase Inhibitors | ALOX15, ALOX15B, ALOX12 | DHODH 361/4885NPSR1 2435/4885CYP3A4 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.